B7ZD04 · SFR1_DANRE
- ProteinSwi5-dependent recombination DNA repair protein 1 homolog
- Genesfr1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids201 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Cellular Component | Swi5-Sfr1 complex | |
Molecular Function | nuclear receptor coactivator activity | |
Biological Process | double-strand break repair via homologous recombination | |
Biological Process | positive regulation of DNA-templated transcription |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSwi5-dependent recombination DNA repair protein 1 homolog
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionB7ZD04
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000406977 | 1-201 | Swi5-dependent recombination DNA repair protein 1 homolog | |||
Sequence: METTPIKPTAADETTPSAEQSSNRSSTAKPMSASLREKLKRSRHSFKSPLSVVKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDSNHTAELPSQQCEALRKAVKERTETLRRLKMVKMYRKKNDLNELQRLTDKWRSCAQSVLYELQRELATGGKQASLSQLIDSFGINDKLLHFDRTEEDFTDT |
Proteomic databases
Expression
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for compositional bias, region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-32 | Polar residues | ||||
Sequence: METTPIKPTAADETTPSAEQSSNRSSTAKPMS | ||||||
Region | 1-111 | Disordered | ||||
Sequence: METTPIKPTAADETTPSAEQSSNRSSTAKPMSASLREKLKRSRHSFKSPLSVVKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDSNHTAELPSQQ | ||||||
Compositional bias | 53-101 | Basic and acidic residues | ||||
Sequence: VKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDS | ||||||
Coiled coil | 109-131 | |||||
Sequence: SQQCEALRKAVKERTETLRRLKM |
Sequence similarities
Belongs to the SFR1/MEI5 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length201
- Mass (Da)23,066
- Last updated2009-03-03 v1
- Checksum25739440AD320360
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-32 | Polar residues | ||||
Sequence: METTPIKPTAADETTPSAEQSSNRSSTAKPMS | ||||||
Sequence conflict | 30 | in Ref. 2; AAI33893 | ||||
Sequence: P → S | ||||||
Compositional bias | 53-101 | Basic and acidic residues | ||||
Sequence: VKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDS | ||||||
Sequence conflict | 185 | in Ref. 2; AAI33893 | ||||
Sequence: N → D |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL929005 EMBL· GenBank· DDBJ | CAX14339.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC133892 EMBL· GenBank· DDBJ | AAI33893.1 EMBL· GenBank· DDBJ | mRNA |