NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.
- AnnotationNEK11 controls degradation of CDC25A by directly phosphorylating CDC25A on residues whose phosphorylation is required for beta-TrCP mediated CDC25A polyubiquitylation and degradation.
- CategoriesFunction, PTM / Processing, Interaction
- SourceGeneRif: 79858