Association of mRNA Expression Levels of LRP1 and Actin-Binding Proteins with the Development of Laryngeal and Laryngopharyngeal Squamous Cell Carcinoma.
Ezrin protein expression is a promising biomarker in estimating the outcome of stage II colorectal cancer patients. When combined with microsatellite status its ability in predicting disease outcome is further improved
3-dimensional cell cultures were found to mimic different tumor sites and be applicable as a model. The in vitro results concur with the clinical specimen analysis suggesting that in ovarian carcinoma the role of ezrin in disease progression is more pronounced than that of p130Cas.
Our findings have important potential implications demonstrating that together with clinical prognostic factors such as radiotherapy and age CXCR4 and IGF-1R negatively influences survival in patients with localized SS.
Ezrin and moesin expression is related to LSCC invasion and metastasis and may be important molecular markers for predicting prognosis and therapeutic targets in LSCC patients
The results from this study validate previous findings of reduced membranous ezrin expression in urothelial bladder cancer being associated with unfavourable clinicopathological characteristics and an impaired survival.
Genetic variations and single nucleotide polymorphisms in the gene EZR possibly contribute to the development of age-related cataracts in the Chinese population.
Ezrin is not associated with the histologic response to chemotherapy in patients with osteosarcoma whereas Ezrin positivity was associated with a lower 2-year survival rate regarding risk of death at 2 years.
panel consisting of moderate/strong expression of CA IX positive HIF-1alpha expression and negative/weak GLUT-1 expression in operative samples and negative/weak ezrin expression in biopsies was associated with 47.5-fold risk of death from this disease
In CNE2 cells the DNA sequence upstream of the ezrin promoter could exhibit transcriptional activation and enhancement in a position- and orientation-dependent manner.
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