B7Q5K1 · QTRT2_IXOSC
- ProteinQueuine tRNA-ribosyltransferase accessory subunit 2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids394 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 336 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 338 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 341 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 367 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | metal ion binding | |
Molecular Function | tRNA-guanosine(34) queuine transglycosylase activity | |
Biological Process | tRNA-guanine transglycosylation |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameQueuine tRNA-ribosyltransferase accessory subunit 2
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Ixodinae > Ixodes
Accessions
- Primary accessionB7Q5K1
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000383944 | 1-394 | Queuine tRNA-ribosyltransferase accessory subunit 2 | ||
Proteomic databases
Interaction
Subunit
Heterodimer of a catalytic subunit and an accessory subunit.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length394
- Mass (Da)43,748
- Last updated2009-02-10 v1
- Checksum5B43C9FACCA6E866
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS861789 EMBL· GenBank· DDBJ | EEC14123.1 EMBL· GenBank· DDBJ | Genomic DNA |