B7LMD5 · QUEC_ESCF3
- Protein7-cyano-7-deazaguanine synthase
- GenequeC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids231 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).
Catalytic activity
- 7-carboxy-7-deazaguanine + NH4+ + ATP = 7-cyano-7-deazaguanine + ADP + phosphate + H2O + H+
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 8-18 | ATP (UniProtKB | ChEBI) | |||
Binding site | 188 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 197 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 200 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 203 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ligase activity, forming carbon-nitrogen bonds | |
Molecular Function | zinc ion binding | |
Biological Process | queuosine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name7-cyano-7-deazaguanine synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionB7LMD5
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000186599 | 1-231 | 7-cyano-7-deazaguanine synthase | ||
Structure
Sequence
- Sequence statusComplete
- Length231
- Mass (Da)25,491
- Last updated2009-02-10 v1
- Checksum6100FFD03AB51E3D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CU928158 EMBL· GenBank· DDBJ | CAQ90068.1 EMBL· GenBank· DDBJ | Genomic DNA |