B7LMD5 · QUEC_ESCF3

Function

function

Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ0).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site8-18ATP (UniProtKB | ChEBI)
Binding site188Zn2+ (UniProtKB | ChEBI)
Binding site197Zn2+ (UniProtKB | ChEBI)
Binding site200Zn2+ (UniProtKB | ChEBI)
Binding site203Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionligase activity, forming carbon-nitrogen bonds
Molecular Functionzinc ion binding
Biological Processqueuosine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    7-cyano-7-deazaguanine synthase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine synthase
    • PreQ(0) synthase
    • Queuosine biosynthesis protein QueC

Gene names

    • Name
      queC
    • Ordered locus names
      EFER_2573

Organism names

Accessions

  • Primary accession
    B7LMD5

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001865991-2317-cyano-7-deazaguanine synthase

Structure

Family & Domains

Sequence similarities

Belongs to the QueC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    25,491
  • Last updated
    2009-02-10 v1
  • Checksum
    6100FFD03AB51E3D
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU928158
EMBL· GenBank· DDBJ
CAQ90068.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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