B7FA90 · HPT1_ORYSJ
- ProteinProbable homogentisate phytyltransferase 1, chloroplastic
- GeneHPT1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids404 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Involved in the synthesis of tocopherol (vitamin E). Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydroquinone (By similarity).
Catalytic activity
- phytyl diphosphate + homogentisate + H+ = 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate
Pathway
Cofactor biosynthesis; tocopherol biosynthesis.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Molecular Function | homogentisate phytyltransferase activity | |
Biological Process | vitamin E biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable homogentisate phytyltransferase 1, chloroplastic
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa
Accessions
- Primary accessionB7FA90
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 119-139 | Helical | ||||
Sequence: TVIGTALSIVSVSLLAVENLS | ||||||
Transmembrane | 144-164 | Helical | ||||
Sequence: LFLTGLLEAVVAALFMNIYIV | ||||||
Transmembrane | 184-204 | Helical | ||||
Sequence: LASGEYSPATGVALVSAFAAM | ||||||
Transmembrane | 216-238 | Helical | ||||
Sequence: PLFLALFISFILGTAYSINLPFL | ||||||
Transmembrane | 245-265 | Helical | ||||
Sequence: VVAALCILAVRAVIVQLAFFL | ||||||
Transmembrane | 282-302 | Helical | ||||
Sequence: LIFATAFMTFFSVVIALFKDI | ||||||
Transmembrane | 325-345 | Helical | ||||
Sequence: VFWICVGLLEMAYCVAILMGA | ||||||
Transmembrane | 348-368 | Helical | ||||
Sequence: ACLWSKYATVVGHAILAAILW | ||||||
Transmembrane | 382-402 | Helical | ||||
Sequence: ITSFYMFIWKLFYAEYLLIPL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-77 | Chloroplast | ||||
Sequence: MDSLRLRPSLLAARAPGAASLPPLRRDHFLPPLCSIHRNGKRPVSLSSQRTQGPSFDQCQKFFGWKSSHHRIPHRPT | ||||||
Chain | PRO_0000409870 | 78-404 | Probable homogentisate phytyltransferase 1, chloroplastic | |||
Sequence: SSSADASGQPLQSSAEAHDSSSIWKPISSSLDAFYRFSRPHTVIGTALSIVSVSLLAVENLSDVSPLFLTGLLEAVVAALFMNIYIVGLNQLFDIEIDKVNKPTLPLASGEYSPATGVALVSAFAAMSFGLGWAVGSQPLFLALFISFILGTAYSINLPFLRWKRSAVVAALCILAVRAVIVQLAFFLHIQTFVFRRPAVFTRPLIFATAFMTFFSVVIALFKDIPDIEGDRIFGIKSFSVRLGQKKVFWICVGLLEMAYCVAILMGATSACLWSKYATVVGHAILAAILWNRSRSIDLTSKTAITSFYMFIWKLFYAEYLLIPLVR |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 68-96 | Disordered | ||||
Sequence: SHHRIPHRPTSSSADASGQPLQSSAEAHD | ||||||
Compositional bias | 77-96 | Polar residues | ||||
Sequence: TSSSADASGQPLQSSAEAHD |
Sequence similarities
Belongs to the UbiA prenyltransferase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length404
- Mass (Da)44,501
- Last updated2009-02-10 v1
- Checksum65B7E822C583A326
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 77-96 | Polar residues | ||||
Sequence: TSSSADASGQPLQSSAEAHD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP004803 EMBL· GenBank· DDBJ | BAD37835.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AP005760 EMBL· GenBank· DDBJ | BAD38343.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AP008212 EMBL· GenBank· DDBJ | BAF20174.2 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AP014962 EMBL· GenBank· DDBJ | BAS98961.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK243323 EMBL· GenBank· DDBJ | BAH01538.1 EMBL· GenBank· DDBJ | mRNA |