B6ZK08 · B6ZK08_9EUKA
- ProteinGlyceraldehyde-3-phosphate dehydrogenase
- Genegap
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids353 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-glyceraldehyde 3-phosphate + NAD+ + phosphate = (2R)-3-phospho-glyceroyl phosphate + H+ + NADH
Pathway
Carbohydrate biosynthesis; Calvin cycle.
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 29 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 133 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 164-166 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: SCT | ||||||
Active site | 165 | Nucleophile | ||||
Sequence: C | ||||||
Site | 192 | Activates thiol group during catalysis | ||||
Sequence: H | ||||||
Binding site | 195 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 223-224 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: TG | ||||||
Binding site | 247 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 335 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | |
Molecular Function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlyceraldehyde-3-phosphate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metamonada > Parabasalia > Trichonymphida > Trichonymphidae > Trichonympha
Accessions
- Primary accessionB6ZK08
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-165 | Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding | ||||
Sequence: NGFGSIGRLVFRAIFELYPTECQVVAIHDLCPILTNVHLLKYDSAHGRFKGDVKVGADGKSFICSSGSTSWTVQNLSEKVGPSELPWAELGVDFVLESTGFYKTAFKADESGKVTTDGYDGHIKAGAKKVVLSVPASDKIDCTLVCGVNDEDLTPDVKCISNASC |
Sequence similarities
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length353
- Mass (Da)37,916
- Last updated2009-02-10 v1
- Checksum1D1A8FE42013E697
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: N |