B6WWP3 · B6WWP3_9BACT

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site511Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Molecular Functionmonooxygenase activity
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      DESPIG_02512

Organism names

  • Taxonomic identifier
  • Strain
    • ATCC 29098
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Desulfovibrio

Accessions

  • Primary accession
    B6WWP3

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue112N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain87-354Orn/DAP/Arg decarboxylase 2 N-terminal
Domain380-460Arginine decarboxylase helical bundle
Domain589-642Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    644
  • Mass (Da)
    72,739
  • Last updated
    2009-01-20 v1
  • Checksum
    D2B968F6414CE5C9
MLEAQELAKNRALQQWRVEDSIELYGIRNWGAGFFTVSDEGDVVVCPQGPKGPQISIPEIISGLRERGYDMPVLLRVENILDSRIASLHESFRKAIKNLNYQGQYRGVFPIKVNQQQQVVEKIAQFGSRYHHGLEVGSKAELIAAVSLMRDTEACIVCNGYKDEEFIDLGLQAQRLGFNLFFVLEMPSELDVLLSRSRELGIRPNIGVRAKLSVKASGHWTDSGGERSTFGLSPAQIVDVVDKLKACDMLDCFRLLHYHLGSQVSNIRDIRTGVMEGARLYVGLVQEGAPMGYLDLGGGLAVDYDGSHTNYISSRNYNLDEYSADIVEAIMSILDEQQVPHPHIITESGRATVAYYSVLLFNVLDVSAVEEAQLPAELPEDTPEPVLNMREVYGNISLRNLQECYNDAIYYRDEMRKLFSTGRVNLRQRTLSERFFWAIIMRIAQEKVKLKTVPRDLQDIDVSLADIYYGNFSVFQSLPDSWAIDQLFPVMPVHRLNEFPSRQGIISDITCDSDGRIDHFIDPQGLKTTLDLHPLKDGEEYYLGVFLVGAYQETLGDLHNLMGDTNVVSIRVNPDGGYEYVREIRGDSVADILSYVEYDPRRILDDLRATAERAVRAGRLTPSDRFAVLQAFEDGLRGYTYFER

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ABXU01000074
EMBL· GenBank· DDBJ
EEB32660.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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