B6VKI4 · B6VKI4_PHOAA
- ProteinAminomethyltransferase
- GenegcvT
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids367 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The glycine cleavage system catalyzes the degradation of glycine.
Catalytic activity
- (6S)-5,6,7,8-tetrahydrofolate + N6-[(R)-S8-aminomethyldihydrolipoyl]-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N6-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 196 | substrate | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | glycine cleavage complex | |
Molecular Function | aminomethyltransferase activity | |
Molecular Function | methyltransferase activity | |
Molecular Function | transaminase activity | |
Biological Process | glycine decarboxylation via glycine cleavage system | |
Biological Process | methylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminomethyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Photorhabdus
Accessions
- Primary accessionB6VKI4
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
The glycine cleavage system is composed of four proteins: P, T, L and H.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-254 | Aminomethyltransferase folate-binding | ||||
Sequence: LYDQHLACGARMVDFHGWMMPLHYGSQMDEHHTVRTDAGMFDVSHMTIVDLHGTGCRDFLRYLLANDIAKLTEKGKALYTGMLNASGGVIDDLIVYYFSHDFYRMVVNSATREKDLAWINEHATHYSVDIQVRDDLALIAIQGPEAQAKVQSLLNDEQKQAIAGMKPFFGIQADELFIATTGYTGEAGYEIAMPKEQAANFWQKLLSAGIKPAGLGARDTLRLEAGMNLYGQDMDETISPLAANMGWT | ||||||
Domain | 280-357 | Glycine cleavage T-protein C-terminal barrel | ||||
Sequence: QLVGLVMREKGVLRSGLTVSFTDEMGTLHSGVITSGTFSPTLGFSIALARVPQGIGEQAIVQIRHREMPVQVVKPGFV |
Sequence similarities
Belongs to the GcvT family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length367
- Mass (Da)40,699
- Last updated2008-12-16 v1
- ChecksumCE7A20294C1401E6
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FM162591 EMBL· GenBank· DDBJ | CAQ83251.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
FM211044 EMBL· GenBank· DDBJ | CAR66664.1 EMBL· GenBank· DDBJ | Genomic DNA |