B6VHC9 · B6VHC9_UNCAX

  • Protein
    coenzyme-B sulfoethylthiotransferase
  • Gene
    mcrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

coenzyme F430 (UniProtKB | Rhea| CHEBI:60540 )

Pathway

One-carbon metabolism; methyl-coenzyme M reduction; methane from methyl-coenzyme M: step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncoenzyme-B sulfoethylthiotransferase activity
Molecular Functionmetal ion binding
Biological Processmethanogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    coenzyme-B sulfoethylthiotransferase
  • EC number

Gene names

    • Name
      mcrA

Organism names

Accessions

  • Primary accession
    B6VHC9

PTM/Processing

Keywords

Interaction

Subunit

MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-41Methyl-coenzyme M reductase alpha subunit N-terminal
Domain89-215Methyl-coenzyme M reductase alpha subunit C-terminal

Sequence similarities

Belongs to the methyl-coenzyme M reductase alpha subunit family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    254
  • Mass (Da)
    27,364
  • Last updated
    2008-12-16 v1
  • Checksum
    12A31F8A36A444F6
AMQIGMSFIAAYNMCAGEAAVADLAFAAKHAAAIQMAEMLPARRARSPNEPGGLSFGYCADMVQKMRVKPDDPVLYTLEVVACGTMLYDQIWLGSYMSGGVGFTQYATAAYTNDVLDDFTYYGYDYALNKYGDDGTAPNDLATATDLATEVTLNGMECYEDYPTLLEDHFGGSQRAGILAAASACTTGIATGNAQVALSAWYMSMYLHKEGWGRLGFFGYDLQDQCGATNVCSYQGDEGCCLELRGANYPNYAM

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue254

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ403598
EMBL· GenBank· DDBJ
ACJ11566.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ403605
EMBL· GenBank· DDBJ
ACJ11573.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ403617
EMBL· GenBank· DDBJ
ACJ11585.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ403640
EMBL· GenBank· DDBJ
ACJ11608.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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