B6T5Z6 · ERB46_MAIZE
- ProteinEthylene-responsive transcription factor WIN1
- GeneEREB46
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids213 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Promotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis, particularly promoting very-long-chain waxes formation (PubMed:35696901).
Confers drought resistance (PubMed:35696901).
Acts as a transcriptional activator binding directly to promoter regions of CER2, CER3.2 and KCS1, wax biosynthesis-related genes (PubMed:35696901).
Binds to the GCC-box pathogenesis-related promoter element (By similarity).
May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Confers drought resistance (PubMed:35696901).
Acts as a transcriptional activator binding directly to promoter regions of CER2, CER3.2 and KCS1, wax biosynthesis-related genes (PubMed:35696901).
Binds to the GCC-box pathogenesis-related promoter element (By similarity).
May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 15-72 | AP2/ERF | ||||
Sequence: KFRGVRQRHWGSWVSEIRHPLLKRRVWLGTFETAEEAARAYDEAAVLMSGRNAKTNFP |
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | sequence-specific DNA binding | |
Biological Process | abscisic acid-activated signaling pathway | |
Biological Process | cuticle development | |
Biological Process | ethylene-activated signaling pathway | |
Biological Process | positive regulation of DNA-templated transcription | |
Biological Process | positive regulation of response to water deprivation | |
Biological Process | positive regulation of wax biosynthetic process | |
Biological Process | response to abscisic acid | |
Biological Process | response to osmotic stress | |
Biological Process | response to water deprivation |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameEthylene-responsive transcription factor WIN1
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea
Accessions
- Primary accessionB6T5Z6
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Reduced amounts of C24/C32 fatty acids, C32/C34 aldehydes, C32/C34 1-alcohols and C31 alkanes in leaves leading to decreased epicuticular wax level and increased cuticle permeability, thus conferring a reduced drought tolerance.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 2 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000459248 | 1-213 | Ethylene-responsive transcription factor WIN1 | |||
Sequence: MTENLHSRKMVQPKKFRGVRQRHWGSWVSEIRHPLLKRRVWLGTFETAEEAARAYDEAAVLMSGRNAKTNFPIQRSSTGEPTPAAGRDARSNFSSGSSTTNLSQILSAKLRKCCKAPSPSLTCLRLDPEKSHIGVWQKRAGARADSNWVMTVELNKDAASTDAASQSTSATTAPPATPMDEEERIALQMIEELLSSSSPASPSNGDDQGRFII |
Proteomic databases
Expression
Tissue specificity
Mostly expressed in roots, stems and anthers, and, to a lower extent, in leaves, seeds and silks.
Induction
Induced by drought, osmotic stress and, transiently by abscisic acid (ABA).
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 70-99 | Disordered | ||||
Sequence: NFPIQRSSTGEPTPAAGRDARSNFSSGSST | ||||||
Compositional bias | 159-175 | Polar residues | ||||
Sequence: ASTDAASQSTSATTAPP | ||||||
Region | 159-213 | Disordered | ||||
Sequence: ASTDAASQSTSATTAPPATPMDEEERIALQMIEELLSSSSPASPSNGDDQGRFII | ||||||
Compositional bias | 191-205 | Polar residues | ||||
Sequence: EELLSSSSPASPSNG |
Sequence similarities
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length213
- Mass (Da)23,355
- Last updated2008-12-16 v1
- Checksum9F3CCAC88E09D05F
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A804PG33 | A0A804PG33_MAIZE | 100282301 | 187 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 159-175 | Polar residues | ||||
Sequence: ASTDAASQSTSATTAPP | ||||||
Compositional bias | 191-205 | Polar residues | ||||
Sequence: EELLSSSSPASPSNG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KJ727837 EMBL· GenBank· DDBJ | AIB05328.1 EMBL· GenBank· DDBJ | mRNA | ||
CM000781 EMBL· GenBank· DDBJ | AQK69487.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NCVQ01000006 EMBL· GenBank· DDBJ | PWZ21889.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
EU960411 EMBL· GenBank· DDBJ | ACG32529.1 EMBL· GenBank· DDBJ | mRNA |