B6QV51 · B6QV51_TALMQ

Function

function

Catalyzes the NAD+-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, site.

140650100150200250300350400
Type
IDPosition(s)Description
Binding site137substrate
Binding site163substrate
Binding site218-219NAD+ (UniProtKB | ChEBI)
Binding site239NAD+ (UniProtKB | ChEBI)
Binding site274-278NAD+ (UniProtKB | ChEBI)
Binding site300NAD+ (UniProtKB | ChEBI)
Site302Important for catalytic activity
Binding site326NAD+ (UniProtKB | ChEBI)
Site355Important for catalytic activity
Binding site355-358NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionformate dehydrogenase (NAD+) activity
Molecular FunctionNAD binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processformate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formate dehydrogenase
  • EC number
  • Short names
    FDH
  • Alternative names
    • NAD-dependent formate dehydrogenase

Gene names

    • ORF names
      PMAA_011780

Organism names

Accessions

  • Primary accession
    B6QV51

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain77-172D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Domain173-343D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    406
  • Mass (Da)
    44,706
  • Last updated
    2008-12-16 v1
  • MD5 Checksum
    F68A73289F27A392809603F97BC0BFE4
MVFSRSIPRALQRPATSLLAIPARQWRAPVFSGVRTLTASAPRQGKVLMVLYDGGEHAKQQPGLLGTTENELGIRKWLEDHGHTLVTTSDKEGPDSVFEKELVDAEVIITTPFHPGYLTAERLAKAKKLKLAVTAGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILTLVRNFVPAHDQIRNGGWDVAAVAKNEYDLENKVVGTVAVGRIGERVLRRLKPFDCKELLYYDYQPLKPEVEKEIGCRRVDTLEEMLAQCDVVTINCPLHEKTKGLFNKELISKMKPGSWLVNTARGAIVVKEDVAEAVKSGHLRGYGGDVWFPQPAPKDHPLRYVEGPWGGGNAMVPHMSGTSIDAQIRYAEGTKKILESYFSGRHDYRPEDLIVHNGDYATKAYGQRK

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
B6QV50B6QV50_TALMQPMAA_011780363

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS995906
EMBL· GenBank· DDBJ
EEA18902.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice.
Help