B6Q8Y0 · B6Q8Y0_TALMQ

Function

function

Interconversion of serine and glycine.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

One-carbon metabolism; tetrahydrofolate interconversion.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Molecular Functionglycine hydroxymethyltransferase activity
Molecular Functionmethyltransferase activity
Molecular Functionpyridoxal phosphate binding
Biological Processglycine biosynthetic process from serine
Biological Processmethylation
Biological Processtetrahydrofolate interconversion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine hydroxymethyltransferase
  • EC number

Gene names

    • ORF names
      PMAA_070220

Organism names

Accessions

  • Primary accession
    B6Q8Y0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue296N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias32-47Polar residues
Region32-56Disordered
Domain65-468Serine hydroxymethyltransferase-like

Sequence similarities

Belongs to the SHMT family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    535
  • Mass (Da)
    59,032
  • Last updated
    2008-12-16 v1
  • MD5 Checksum
    9A60EEBAEB095D99634CED4C37763399
MSFNRCSRQASKLLATNGSSLRAATSTLYRSQRAASIHPSQVASQKRNVSDTHHDSQQKLLSTHLEEADPTIFAILQKEKQRQKHFINLIPSENFTSQAVLDALGSVMQNKYSEGYPGARYYGGNEFIDQAESLCQKRALETFRLNPDEWGVNVQALSGSPANLYAYSALLNTHDRLMGLDLPHGGHLSHGYQIPNKKISFISKYFETLPYRLDESTGLINYDQLEELANIYRPKLIVAGTSAYSRLIDYARMRKITDSIGAYLLSDMAHISGLVAADVIPSPFSYSDVVTTTTHKSLRGPRGAMIFYRKGVRRTDKKGNQEMYDLENPINASVFPGHQGGPHNHTITALAVALGQAQTKEFREYQLTVLENAKALSDRLGNSVNEGGLGYNIVSGGTDNHLVLVDLKNRGVDGARVERVLELCGVAANKNTVPGDKSALKPGGLRIGTPAMTSRGFQPEDFRRVGDIVDRAVTITQKLDKAAKESAEAKGRKNPGVLKAFTEYVGNGDDISEIVQLRREVEDWVGTFDVPWKDE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias32-47Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS995900
EMBL· GenBank· DDBJ
EEA25934.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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