B6HVR6 · NIT2_PENRW

Function

function

Nitrilase that hydrolyzes preferentially 4-cyanopyridine. Is also able to hydrolyze some aliphatic nitriles, such as (R,S)-mandelonitrile.

Catalytic activity

Features

Showing features for active site.

132850100150200250300
TypeIDPosition(s)Description
Active site49Proton acceptor
Active site131
Active site166Nucleophile

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionhydro-lyase activity
Molecular Functionindole-3-acetonitrile nitrilase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nitrilase
  • EC number
  • Alternative names
    • NitPc2

Gene names

    • ORF names
      Pc22g19330ma2m

Organism names

Accessions

  • Primary accession
    B6HVR6

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004321801-328Nitrilase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain9-286CN hydrolase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    328
  • Mass (Da)
    36,809
  • Last updated
    2008-12-16 v1
  • Checksum
    AA68D3B2A6F1AD61
MTAPVERRVRVAAIQAEPVWNDLQGGVNKVISLLGDVGKEGANVVGFPEVFIPGYPWSIFTATPLDNAPFMEEYFHNSLAVDSDEMRRIQAAVKENGTFCVLGFSERYQGSLYISQVFINTDGQIVHHRRKTKPTHVERAYWGTGEGDSLKCVVDSPFGRIGGLNCWEHTQPLLRYYEYQQDVDIHVASWPVLWDRPESVGSRWPYFITGDMSSRLSQVMAFEGTCFVLVCTQVMSEENFDKNKVRDVEHIQGTGGGFSAIFGPGGEPIATMPSDKEGILYANVDVNDKLRAKQWLDVVGHYSRPDLLSLRVNTHPSKPVFFAEEPEK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM920437
EMBL· GenBank· DDBJ
CAP99221.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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