B6DTP5 · B6DTP5_RAT

  • Protein
    Probable ATP-dependent RNA helicase DDX5
  • Gene
    Ddx5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcatalytic step 2 spliceosome
Cellular Componentcytoplasm
Cellular Componentnuclear speck
Cellular Componentnucleolus
Cellular Componentnucleus
Cellular Componentribonucleoprotein complex
Molecular FunctionATP binding
Molecular Functioncalcium-dependent protein binding
Molecular Functioncalmodulin binding
Molecular Functionenzyme binding
Molecular Functionhydrolase activity
Molecular FunctionMH2 domain binding
Molecular FunctionmRNA 3'-UTR binding
Molecular Functionnuclear androgen receptor binding
Molecular Functionpre-mRNA binding
Molecular Functionprimary miRNA binding
Molecular Functionpromoter-specific chromatin binding
Molecular FunctionR-SMAD binding
Molecular Functionribonucleoprotein complex binding
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Molecular FunctionSMAD binding
Molecular Functiontranscription coregulator activity
Biological Processalternative mRNA splicing, via spliceosome
Biological Processandrogen receptor signaling pathway
Biological ProcessBMP signaling pathway
Biological Processcircadian rhythm
Biological Processepithelial to mesenchymal transition
Biological Processestrogen receptor signaling pathway
Biological Processintrinsic apoptotic signaling pathway by p53 class mediator
Biological ProcessmiRNA transcription
Biological ProcessmRNA transcription
Biological Processmyoblast differentiation
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processnuclear-transcribed mRNA catabolic process
Biological Processpositive regulation of DNA damage response, signal transduction by p53 class mediator
Biological Processpositive regulation of DNA-templated transcription
Biological Processprimary miRNA processing
Biological Processprotein import into nucleus
Biological Processregulation of alternative mRNA splicing, via spliceosome
Biological Processregulation of androgen receptor signaling pathway
Biological Processregulation of osteoblast differentiation
Biological Processregulation of skeletal muscle cell differentiation
Biological Processregulation of transcription by RNA polymerase II
Biological Processregulation of viral genome replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable ATP-dependent RNA helicase DDX5
  • EC number
  • Alternative names
    • DEAD box protein 5

Gene names

    • Name
      Ddx5

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    B6DTP5

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain, motif.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-39Disordered
Domain94-122DEAD-box RNA helicase Q
Motif94-122Q motif
Domain125-300Helicase ATP-binding
Domain328-475Helicase C-terminal
Region477-504Disordered

Sequence similarities

Belongs to the DEAD box helicase family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    614
  • Mass (Da)
    69,112
  • Last updated
    2008-11-25 v1
  • Checksum
    FEB55FB46FAF753C
MSSYSSDRDRGRDRGFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSDVANMHNGMNQQAYAYPATAAAAPMIGYPMPTGYS

Features

Showing features for compositional bias, non-terminal residue.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Non-terminal residue614

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ168767
EMBL· GenBank· DDBJ
ACI04543.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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