B6CHW7 · B6CHW7_9ANNE
- ProteinSuperoxide dismutase [Cu-Zn]
- GeneSOD1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids153 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity
- 2 H+ + 2 superoxide = H2O2 + O2
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 copper ion per subunit.
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 45 | Cu+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 45 | Cu2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 47 | Cu+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 47 | Cu2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 62 | Cu2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 62 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 70 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 79 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 82 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 119 | Cu+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 119 | Cu2+ (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | copper ion binding | |
Molecular Function | superoxide dismutase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuperoxide dismutase [Cu-Zn]
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Annelida > Polychaeta > Sedentaria > Canalipalpata > Terebellida > Terebelliformia > Alvinellidae > Alvinella
Accessions
- Primary accessionB6CHW7
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 56↔145 | |||||
Sequence: CTSAGGHFNPHGKEHGAPEDENRHAGDLGNVVAGEDGKAVINMKDKLVKLTGPDSVIGRTLVVHVDEDDLGRGGHEQSKITGNAGGRLAC |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-148 | Superoxide dismutase copper/zinc binding | ||||
Sequence: VTGTIHLKEEGDMVTVTGEITGLTPGKHGFHVHEFGDNTNGCTSAGGHFNPHGKEHGAPEDENRHAGDLGNVVAGEDGKAVINMKDKLVKLTGPDSVIGRTLVVHVDEDDLGRGGHEQSKITGNAGGRLACGVI |
Sequence similarities
Belongs to the Cu-Zn superoxide dismutase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length153
- Mass (Da)15,829
- Last updated2008-11-25 v1
- Checksum22DB3EDAF4B17E47
Keywords
- Technical term