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B6C9C3 · B6C9C3_ONCCL

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 2
  • EC number

Gene names

    • Name
      ND2

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    B6C9C3

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane60-81Helical
Transmembrane93-116Helical
Transmembrane136-166Helical
Transmembrane178-196Helical
Transmembrane202-219Helical
Transmembrane240-261Helical
Transmembrane281-305Helical
Transmembrane317-339Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-288NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain290-343NADH dehydrogenase subunit 2 C-terminal

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    349
  • Mass (Da)
    37,783
  • Last updated
    2008-11-25 v1
  • MD5 Checksum
    1FC169558AE89221B440943AC42080CB
MNPYVLTILLSSLGLGTVLTFASSHWLLAWMGLEINTLAIIPIMAQQHHPRAIEATTKYFLTQATAAAMILFASTTNAWLMGEWEIHQLSHPLATTTVMLALALKLGLAPVHFWLPEVLQGLELTTGLVLSTWQKLAPFALMIQVAPTINSPLLVAIGLLSTLVGGWGGLNQTQLRKILAYSSIAHLGWMVLILQFAPSLTLLSLSLYIIMTSSAFLTLKTNNALTINTLATSWTKSPTLAALAALMLLSLGGLPPLSGFMPKWLILQELTKQGLPLSATLAAMTALLSLYFYLRLCYALTLTIYPNTLTATAPWRLNFTMITLPLSIITILALGLLPLTPAVTAMLTL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU091112
EMBL· GenBank· DDBJ
ABV89826.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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