B5Z8M0 · FLUC_HELPG
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids130 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 77 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 80 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Helicobacteraceae > Helicobacter
Accessions
- Primary accessionB5Z8M0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 3-23 | Helical | |||
Transmembrane | 38-58 | Helical | |||
Transmembrane | 67-87 | Helical | |||
Transmembrane | 102-122 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000125135 | 1-130 | Fluoride-specific ion channel FluC | ||
Structure
Sequence
- Sequence statusComplete
- Length130
- Mass (Da)14,135
- Last updated2008-11-25 v1
- ChecksumACB236AAECBDC977
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001173 EMBL· GenBank· DDBJ | ACI27919.1 EMBL· GenBank· DDBJ | Genomic DNA |