B5Z4G1 · KDUI_ECO5E
- Protein4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
- GenekduI
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids278 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
Catalytic activity
- 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 4/5.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity | |
Molecular Function | zinc ion binding | |
Biological Process | pectin catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionB5Z4G1
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000131879 | 1-278 | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase | |||
Sequence: MDVRQSIHSAHAKTLETQGLRNEFLVEKVFVADEYTMVYSHIDRIIIGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR |
Interaction
Subunit
Homohexamer.
Structure
Sequence
- Sequence statusComplete
- Length278
- Mass (Da)31,090
- Last updated2008-11-25 v1
- ChecksumB8E4098A31BEB6A2
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001164 EMBL· GenBank· DDBJ | ACI38163.1 EMBL· GenBank· DDBJ | Genomic DNA |