B5YS30 · KBAY_ECO5E

Function

function

Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate metabolism; D-tagatose 6-phosphate degradation; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site82Proton donor
Binding site83Zn2+ (UniProtKB | ChEBI); catalytic
Binding site180Zn2+ (UniProtKB | ChEBI); catalytic
Binding site181dihydroxyacetone phosphate (UniProtKB | ChEBI)
Binding site208Zn2+ (UniProtKB | ChEBI); catalytic
Binding site209-211dihydroxyacetone phosphate (UniProtKB | ChEBI)
Binding site230-233dihydroxyacetone phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functiontagatose-bisphosphate aldolase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate metabolic process
Biological ProcessD-tagatose 6-phosphate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-tagatose-1,6-bisphosphate aldolase subunit KbaY
  • EC number
  • Short names
    TBPA
    ; TagBP aldolase
  • Alternative names
    • D-tagatose-bisphosphate aldolase class II
    • Ketose 1,6-bisphosphate aldolase class II
    • Tagatose-bisphosphate aldolase

Gene names

    • Name
      kbaY
    • Ordered locus names
      ECH74115_4454

Organism names

Accessions

  • Primary accession
    B5YS30

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001404291-286D-tagatose-1,6-bisphosphate aldolase subunit KbaY

Interaction

Subunit

Homotetramer. Forms a complex with KbaZ.

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    31,294
  • Last updated
    2008-11-25 v1
  • Checksum
    CAA42DF05C2B918B
MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001164
EMBL· GenBank· DDBJ
ACI38706.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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