B5XLI1 · GUAC_STRPZ
- ProteinGMP reductase
- GeneguaC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Catalytic activity
- IMP + NH4+ + NADP+ = GMP + NADPH + 2 H+
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 176 | Thioimidate intermediate | |||
Binding site | 205-228 | NADP+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | GMP reductase complex | |
Molecular Function | GMP reductase activity | |
Biological Process | purine nucleotide metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGMP reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionB5XLI1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000146144 | 1-327 | GMP reductase | ||
Structure
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)35,915
- Last updated2008-11-25 v1
- Checksum1733CADB2F4A4A2D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000829 EMBL· GenBank· DDBJ | ACI61193.1 EMBL· GenBank· DDBJ | Genomic DNA |