B5XEE5 · B5XEE5_SALSA
- ProteinRegucalcin
- GeneRGN
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids298 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-glucono-1,5-lactone + H2O = D-gluconate + H+
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 divalent metal cation per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 17 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 100 | substrate | ||||
Sequence: R | ||||||
Binding site | 102 | substrate | ||||
Sequence: N | ||||||
Binding site | 120 | substrate | ||||
Sequence: E | ||||||
Binding site | 153 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Active site | 203 | Proton donor/acceptor | ||||
Sequence: D | ||||||
Binding site | 203 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | calcium ion binding | |
Molecular Function | enzyme regulator activity | |
Molecular Function | gluconolactonase activity | |
Biological Process | L-ascorbic acid biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRegucalcin
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Salmo
Accessions
- Primary accessionB5XEE5
Proteomes
Subcellular Location
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 15-262 | SMP-30/Gluconolactonase/LRE-like region | ||||
Sequence: IGEGPVWEEKEGTLLFVDISGQKIHRWNSTTNQKETVATEKFVGCAVPRRSGGYVIGEGRSFGALDWESKSISTIAVIDEDKPNNRFNDGKVDPAGRLFAGTMAMEERPTVLELKQGSLFSLNKDHIVVKHFNQVDISNGLDWSLDHKTFYYIDSLTYTVEAFNYDINTGSISNRRMVYKMEEGEGIPDGMCIDADGRLWVACYNGGRVIQIDPQTGVRLQTVKLPVDKTTSCCFGGRDYSDLYVTSA |
Sequence similarities
Belongs to the SMP-30/CGR1 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length298
- Mass (Da)32,902
- Last updated2008-11-25 v1
- Checksum8C8CEDC0A4EF7987
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BT049414 EMBL· GenBank· DDBJ | ACI69215.1 EMBL· GenBank· DDBJ | mRNA | ||
BT058644 EMBL· GenBank· DDBJ | ACN10357.1 EMBL· GenBank· DDBJ | mRNA | ||
BT060357 EMBL· GenBank· DDBJ | ACN12717.1 EMBL· GenBank· DDBJ | mRNA |