B5X8J6 · B5X8J6_SALSA
- ProteinHypoxanthine-guanine phosphoribosyltransferase
- GeneHPRT
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphateThis reaction proceeds in the backward direction.
Cofactor
Pathway
Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | hypoxanthine phosphoribosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleotide binding | |
Biological Process | GMP salvage | |
Biological Process | guanine salvage | |
Biological Process | hypoxanthine metabolic process | |
Biological Process | IMP salvage |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHypoxanthine-guanine phosphoribosyltransferase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Salmo
Accessions
- Primary accessionB5X8J6
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length77
- Mass (Da)8,594
- Last updated2008-11-25 v1
- MD5 ChecksumDD24A61989705C2ACABE294D23BF17CF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BT047365 EMBL· GenBank· DDBJ | ACI67166.1 EMBL· GenBank· DDBJ | mRNA |