B5X1G3 · GPHR_SALSA
- ProteinGolgi pH regulator
- Genegpr89
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids455 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Voltage-gated channel that enables the transfer of anions such as iodide, chloride, bromide and fluoride which may function in counter-ion conductance and participates in Golgi acidification.
Catalytic activity
- iodide(out) = iodide(in)
- chloride(in) = chloride(out)
- bromide(in) = bromide(out)
- fluoride(in) = fluoride(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Golgi cisterna membrane | |
Cellular Component | Golgi membrane | |
Cellular Component | monoatomic ion channel complex | |
Molecular Function | voltage-gated monoatomic anion channel activity | |
Biological Process | intracellular pH reduction | |
Biological Process | protein transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameGolgi pH regulator
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Salmo
Accessions
- Primary accessionB5X1G3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 46-66 | Helical | ||||
Sequence: ITFAFSCTMFELIIFEILGAL | ||||||
Transmembrane | 79-99 | Helical | ||||
Sequence: LYVILLVLIFVVPFYIGYFVV | ||||||
Transmembrane | 111-131 | Helical | ||||
Sequence: LFACVVWFTFMYFFWKLGDPF | ||||||
Transmembrane | 150-170 | Helical | ||||
Sequence: VGVIGVTLMALLSGFGAVNCP | ||||||
Transmembrane | 290-310 | Helical | ||||
Sequence: GYFFSIYCVWKIFMATINIVF | ||||||
Transmembrane | 343-363 | Helical | ||||
Sequence: ISFILVGIIIVTSIRGLLITL | ||||||
Transmembrane | 378-398 | Helical | ||||
Sequence: VIVLVLAQIMGMYFVSSVLLM | ||||||
Transmembrane | 425-445 | Helical | ||||
Sequence: WFDVIFLVSALSSILFLYLAH |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000395007 | 1-455 | Golgi pH regulator | |||
Sequence: MSFLMDSVIMFTSQVLFFGFGWLFFMRQLFKDYEVRQYVVQVVFSITFAFSCTMFELIIFEILGALETSSRYFHWKFNLYVILLVLIFVVPFYIGYFVVSNIRLLQRQKLLFACVVWFTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTESDILALERRLLQTMDMIVSKKKRIAMTRRQMYQRGEDQNKQTGFWGMIKSVTSSPPGSENLSLIQQEVDALEELSRQLFLETVDLQATKERIEYSKTFQGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLVLAQIMGMYFVSSVLLMRMSMPLEYRSIVTEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMTP | ||||||
Glycosylation | 180 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 243 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length455
- Mass (Da)53,102
- Last updated2008-11-25 v1
- Checksum9A46A4C30CD07479
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1S2X113 | A0A1S2X113_SALSA | gpr89 | 455 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BT044882 EMBL· GenBank· DDBJ | ACI33144.1 EMBL· GenBank· DDBJ | mRNA |