B5T332 · B5T332_9HYME
- ProteinNADH-ubiquinone oxidoreductase chain 1
- Genenad1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids311 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Catalytic activity
- a ubiquinone + NADH + 5 H+(in) = a ubiquinol + NAD+ + 4 H+(out)
a ubiquinone RHEA-COMP:9565 + CHEBI:57945 + 5 H+ (in)CHEBI:15378= a ubiquinol RHEA-COMP:9566 + CHEBI:57540 + 4 H+ (out)CHEBI:15378
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Biological Process | aerobic respiration |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH-ubiquinone oxidoreductase chain 1
- EC number
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Proctotrupomorpha > Chalcidoidea > Pteromalidae > Pteromalinae > Nasonia
Accessions
- Primary accessionB5T332
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-28 | Helical | |||
Transmembrane | 73-92 | Helical | |||
Transmembrane | 104-126 | Helical | |||
Transmembrane | 147-171 | Helical | |||
Transmembrane | 177-196 | Helical | |||
Transmembrane | 225-249 | Helical | |||
Transmembrane | 255-275 | Helical | |||
Transmembrane | 282-303 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length311
- Mass (Da)36,586
- Last updated2008-11-04 v1
- MD5 ChecksumD8420B4F9FC84DA8550AF8DB61DD9746
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU746614 EMBL· GenBank· DDBJ | ACH81726.1 EMBL· GenBank· DDBJ | Genomic DNA |