B5LUQ4 · FALX1_LITFA

Function

function

Fallaxidin-4.1 shows antibacterial activity against the Gram-positive bacteria L.lactis (MIC=12 uM), M.luteus (MIC=100 uM), S.epidermidis (MIC=100 uM) and S.uberis (MIC=50 uM). No antibacterial activity against the Gram-positive bacteria B.cereus, E.faecalis, L.innocua, S.aureus, or the Gram-negative bacteria E.cloacae and E.coli. Inhibits the formation of NO by neuronal nitric oxide synthase with an IC50 of 13.3 uM.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular region
Biological Processdefense response to bacterium
Biological Processdefense response to Gram-positive bacterium
Biological Processnegative regulation of nitric-oxide synthase activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Preprofallaxidin-1
  • Cleaved into 1 chains

Organism names

Accessions

  • Primary accession
    B5LUQ4

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, propeptide, peptide.

Type
IDPosition(s)Description
Signal1-22
PropeptidePRO_000036170023-46
PeptidePRO_000036170147-67Fallaxidin-4.1

Keywords

Expression

Tissue specificity

Expressed by the skin glands.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region24-46Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    67
  • Mass (Da)
    7,593
  • Last updated
    2008-10-14 v1
  • Checksum
    951B158DAE4EFD25
MASLKKSLFLVLFLGMVSLSICDKEKREGENEEEEEEHEEESEEKRGLLSFLPKVIGVIGHLIHPPS

Mass Spectrometry

Molecular mass is 2,192 Da. Determined by Electrospray.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU912529
EMBL· GenBank· DDBJ
ACH53447.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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