B5KVH4 · 11S1_CARIL

Function

function

Seed storage protein.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionIgE binding
Molecular Functionnutrient reservoir activity
Biological Processseed development
Biological Processseed maturation

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fagales > Juglandaceae > Carya

Accessions

  • Primary accession
    B5KVH4

Phenotypes & Variants

Allergenic properties

Causes an allergic reaction in human. Recombinant protein binds to IgE in 57% of the 28 patients tested allergic to pecan nuts. Acidic chain is more immunoreactive than the basic chain.

Keywords

Protein family/group databases

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_000044854025-31611S globulin seed storage protein 1 acidic chain
Disulfide bond37↔70
Disulfide bond113↔323Interchain (between acidic and basic chains)
ChainPRO_0000448541317-50511S globulin seed storage protein 1 basic chain

Keywords

Expression

Tissue specificity

Expressed in seeds (at protein level) (PubMed:21718052).
Expressed in seeds (PubMed:28121438).

Induction

Up-regulated during nut development.

Developmental stage

Expressed during seed maturation (PubMed:21718052).
Expressed during embryonic development including the water, gel, dough and mature nut stages in the nut cavity tissues including the contents of the central vacuole, endosperm, embryo, placenta, seed coat, ovary packing tissue, developing fruit and cotyledon lobes. Expression increases during the transition from water to gel stage, levels off or decreases slightly from the gel to dough stage and increases again from the dough to mature stage (PubMed:28121438).

Interaction

Subunit

Homohexamer (By similarity).
Each subunit is composed of an acidic and a basic chain derived from a single precursor and linked by a disulfide bond (PubMed:21718052).

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias, motif.

TypeIDPosition(s)Description
Domain42-255Cupin type-1 1
Region118-132IgE-binding
Region193-232Disordered
Compositional bias201-227Basic and acidic residues
Region208-219IgE-binding
Region238-249IgE-binding
Compositional bias282-317Basic and acidic residues
Region282-318Disordered
Motif316-321NGXEET; peptidase recognition motif
Domain329-478Cupin type-1 2

Sequence similarities

Belongs to the 11S seed storage protein (globulins) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    505
  • Mass (Da)
    58,016
  • Last updated
    2008-10-14 v1
  • Checksum
    4B4A57816D3D6D7E
MAKPILLSIYLCLIIVALFNGCLAQSGGRQQHKFGQCQLNRLDALEPTNRIEAEAGVIESWDPNHQQLQCAGVAVVRRTIEPNGLLLPHYSNAPQLVYIARGRGITGVLFPGCPETFEESQRQSQQGQRREFQQDRHQKIRHFREGDIIAFPAGVAHWCYNDGSSPVVAIFLLDTHNNANQLDQNPRNFYLAGNPDDEFRPQGQQEYEQHRRQQQHQQRRGEHGEQQRDLGNNVFSGFDAEFLADAFNVDTETARRLQSENDHRGSIVRVEGRQLQVIRPRWSREEQEHEERKERERERESESERRQSRRGGRDDNGLEETICTLSLRENIGDPSRADIYTEEAGRISTVNSHNLPILRWLQLSAERGALYSDALYVPHWNLNAHSVVYALRGRAEVQVVDNFGQTVFDDELREGQLLTIPQNFAVVKRARDEGFEWVSFKTNENAMVSPLAGRTSAIRALPEEVLVNAFQIPREDARRLKFNRQESTLVRSRSRSSRSERRAEV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias201-227Basic and acidic residues
Compositional bias282-317Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU113051
EMBL· GenBank· DDBJ
ABW86978.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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