B5BU28 · B5BU28_HUMAN
- ProteinCatenin beta-1
- GeneCTNNB1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids781 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | adherens junction | |
Cellular Component | catenin complex | |
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | alpha-catenin binding | |
Molecular Function | cadherin binding | |
Molecular Function | DNA-binding transcription factor binding | |
Molecular Function | protein phosphatase binding | |
Molecular Function | transcription coactivator activity | |
Biological Process | canonical Wnt signaling pathway | |
Biological Process | cell-cell adhesion | |
Biological Process | positive regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCatenin beta-1
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionB5BU28
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 34-48 | Polar residues | ||||
Sequence: GIHSGATTTAPSLSG | ||||||
Region | 34-57 | Disordered | ||||
Sequence: GIHSGATTTAPSLSGKGNPEEEDV | ||||||
Repeat | 151-191 | ARM | ||||
Sequence: RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRS | ||||||
Repeat | 193-236 | ARM | ||||
Sequence: QMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGG | ||||||
Repeat | 235-277 | ARM | ||||
Sequence: GGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAG | ||||||
Repeat | 277-319 | ARM | ||||
Sequence: GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASG | ||||||
Repeat | 319-362 | ARM | ||||
Sequence: GGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGG | ||||||
Repeat | 400-442 | ARM | ||||
Sequence: GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVG | ||||||
Repeat | 442-484 | ARM | ||||
Sequence: GGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNA | ||||||
Repeat | 489-532 | ARM | ||||
Sequence: YGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGA | ||||||
Repeat | 594-636 | ARM | ||||
Sequence: NTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAMEAEGA | ||||||
Region | 705-781 | Disordered | ||||
Sequence: EPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL |
Sequence similarities
Belongs to the beta-catenin family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length781
- Mass (Da)85,515
- Last updated2008-10-14 v1
- Checksum11F8B565A7AEBF43
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 34-48 | Polar residues | ||||
Sequence: GIHSGATTTAPSLSG |