B4TA81 · DGOD_SALHS
- ProteinD-galactonate dehydratase
- GenedgoD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids382 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
Miscellaneous
Reaction proceeds via an anti dehydration.
Catalytic activity
- D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Pathway
Carbohydrate acid metabolism; D-galactonate degradation; D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 1/3.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 183 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Active site | 185 | Proton donor | ||||
Sequence: H | ||||||
Binding site | 209 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 235 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Site | 258 | Increases basicity of active site His | ||||
Sequence: D | ||||||
Active site | 285 | Proton acceptor | ||||
Sequence: H | ||||||
Site | 310 | Transition state stabilizer | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | galactonate dehydratase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | amino acid catabolic process | |
Biological Process | D-galactonate catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameD-galactonate dehydratase
- EC number
- Short namesGalD
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionB4TA81
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000140389 | 1-382 | D-galactonate dehydratase | |||
Sequence: MKITHITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHEFADYLIGKDPARINDLWQVMYRAGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIEKLRGIGFDTFKLNGCEEMGVIDNSRAVDAAVNTVAQIREAFGSEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSRFEFKRVLDAGGLAILQPDLSHAGGITECYKIAGMAEAYDVALAPHCPLGPIALAACLHIDFVSRNAVFQEQSMGIHYNKGAELLDFVKNKEDFSMDGGFFKPLTKPGLGVDIDEARVIELSKSAPDWRNPLWRHADGSVAEW |
Structure
Sequence
- Sequence statusComplete
- Length382
- Mass (Da)42,379
- Last updated2008-09-23 v1
- Checksum51A2D7F9CF9C7DE8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001120 EMBL· GenBank· DDBJ | ACF67521.1 EMBL· GenBank· DDBJ | Genomic DNA |