B4SZR0 · FADJ_SALNS

Function

function

Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.

Catalytic activity

Pathway

Lipid metabolism; fatty acid beta-oxidation.

Features

Showing features for site.

TypeIDPosition(s)Description
Site118Important for catalytic activity
Site140Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-hydroxyacyl-CoA dehydrogenase activity
Molecular Function3-hydroxybutyryl-CoA epimerase activity
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid oxidation complex subunit alpha

Including 2 domains:

  • Recommended name
    Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase
  • EC number
  • Recommended name
    3-hydroxyacyl-CoA dehydrogenase
  • EC number

Gene names

    • Name
      fadJ
    • Ordered locus names
      SNSL254_A2577

Organism names

Accessions

  • Primary accession
    B4SZR0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001859521-715Fatty acid oxidation complex subunit alpha

Interaction

Subunit

Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-190Enoyl-CoA hydratase
Region306-7153-hydroxyacyl-CoA dehydrogenase

Sequence similarities

In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    715
  • Mass (Da)
    77,241
  • Last updated
    2008-09-23 v1
  • Checksum
    90446BCAB2776C64
MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCATHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001113
EMBL· GenBank· DDBJ
ACF61357.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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