B4RLJ8 · B4RLJ8_NEIG2
- ProteinLarge ribosomal subunit assembly factor BipA
- GenebipA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids603 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 14-19 | GTP (UniProtKB | ChEBI) | |||
Binding site | 127-130 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | ribonucleoprotein complex | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | guanosine tetraphosphate binding | |
Molecular Function | ribosome binding | |
Molecular Function | rRNA binding | |
Molecular Function | tRNA binding | |
Biological Process | ribosomal large subunit assembly |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLarge ribosomal subunit assembly factor BipA
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria
Accessions
- Primary accessionB4RLJ8
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-197 | Tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length603
- Mass (Da)67,182
- Last updated2008-09-23 v1
- MD5 ChecksumF74F468B1B6538B8126B8E1A826EDFEC
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001050 EMBL· GenBank· DDBJ | ACF29685.1 EMBL· GenBank· DDBJ | Genomic DNA |