B4N8K5 · B4N8K5_DROWI

Function

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

119102004006008001,0001,2001,4001,6001,800
TypeIDPosition(s)Description
Binding site1150ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentaxon
Cellular Componentinsulin receptor complex
Molecular FunctionATP binding
Molecular Functionidentical protein binding
Molecular Functioninsulin binding
Molecular Functioninsulin receptor activity
Molecular Functioninsulin receptor substrate binding
Biological Processaxon guidance
Biological Processcellular response to starvation
Biological Processcholesterol homeostasis
Biological Processcircadian rhythm
Biological Processdetermination of adult lifespan
Biological Processfemale germ-line stem cell asymmetric division
Biological Processfemale germ-line stem cell population maintenance
Biological Processfemale gonad development
Biological Processfemale mating behavior
Biological Processfollicle cell of egg chamber development
Biological Processgerm-band shortening
Biological Processgerm-line stem-cell niche homeostasis
Biological Processglucose homeostasis
Biological Processimaginal disc growth
Biological Processintestinal stem cell homeostasis
Biological Processlocomotory behavior
Biological Processlymph gland development
Biological Processmale germ-line stem cell asymmetric division
Biological Processmulticellular organism growth
Biological Processnegative regulation of circadian sleep/wake cycle, sleep
Biological Processnegative regulation of entry into reproductive diapause
Biological Processnegative regulation of feeding behavior
Biological Processnegative regulation of macroautophagy
Biological Processnegative regulation of peptide hormone secretion
Biological Processpositive regulation of border follicle cell migration
Biological Processpositive regulation of cell growth
Biological Processpositive regulation of cell size
Biological Processpositive regulation of fat cell proliferation
Biological Processpositive regulation of kinase activity
Biological Processpositive regulation of lipid storage
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of multicellular organism growth
Biological Processpositive regulation of neuroblast proliferation
Biological Processpositive regulation of neuron remodeling
Biological Processpositive regulation of organ growth
Biological Processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processpositive regulation of wound healing
Biological Processprimary spermatocyte growth
Biological Processprotein phosphorylation
Biological Processresponse to anoxia
Biological Processresponse to cocaine
Biological Processresponse to oxidative stress
Biological Processtriglyceride homeostasis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      Dwil\GK12078
    • ORF names
      Dwil_GK12078

Organism names

  • Taxonomic identifier
  • Strain
    • Tucson 14030-0811.24
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    B4N8K5

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1058-1081Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Structure

3D structure databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region48-70Disordered
Region782-848Disordered
Compositional bias800-827Basic and acidic residues
Domain957-1054Fibronectin type-III
Domain1118-1401Protein kinase
Region1531-1621Disordered
Compositional bias1593-1621Polar residues
Region1641-1685Disordered
Region1801-1820Disordered
Region1828-1910Disordered
Compositional bias1837-1899Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,910
  • Mass (Da)
    211,415
  • Last updated
    2016-01-20 v2
  • Checksum
    8A5902CD593896E4
MIIMSLLAMHATAAIQLPPSHQQLSSSHHQYDSNDLGDSLAIFTSSPRIRRDSGNASGNSIGKSGDSGNTQVRLSRNETMCKSMDIRNYATNFNQLTNCTIIEGFLLITLINDAHLLNTTYPLLTEVTEYIIVYRVNNLLSLSQIFPNLSVIRGNSLFDGYALVVYQNRDLQDIGLSKLRAIANGAVRFEKNLSLCFLTTVDWSQIISKNSSEMVSIENRNPTLCPKCPGEIRLSDDGANSGSTEADPLSCKKHTDGKRYCWGSRSCQSFCPKECPDNCYDEHTCCNKACLGGCVRDKNGSLGCISCRYVSIHNNTCLNECPKDYFLYGRRCITAEMCRSIGTKYESTKELKLMHFDGQCTTRCPKGFQIEETTNTCVPCNGTCEKRCEGGQIESGGRAREFYGCTKIGITNGLVISIKRGGPHIMEDLEYGLAKVHTIETYLKVHLTYGLSTLAFFKSLRQIRGNVTFEHRYALYVLENNELEEIWAPNQTVEIANGSVFFHFNPKLCMKTIKTLLPMLPSKPTSFEKTEVAGDSNGNKGSCNTTVLNVKIKSQTDSMALIFVNQSLKFDDLRTFIGYQSFYTKDPYGNATKNSYHPCDESWTASEPVKEDNLMITDLEPYTQYAYYVKTWTISSESQNGLSPIQHFTTLPAQPTLVQKIKARANSSSEIEVQWEPPRSVRGKLKLYLVKAVLTHRDAKLESHQQRNYCWDPLPNNNEDNIIVEKAKVTDKQPTDAADCQCNANSGGPSVGVGGKGANFEQNRREEIEFENALQNFLYVRRQGDQNRTNPAVAPPPKPKDNSIKDDGLLDNAVHKRRRRRRELDFDDDGDDDGDLGMGSVLSRHVRSTETQDDLRNLYAMDNMGATENAEKIRPETWLKETRKSADGTYYEILTQQVGANQTHFVFTNLRHFSLYTISVVACREEVAGSFKPSCGNASPIDKLTRKLENADLVANVTADLESANATRPGVRLRWLAPLNPNGAIVSYTIGYKLQMPDQQELMKCVTAQDYLNLTDGYVVKHLSEGNYSFHVRANSMAGDGIFSELVYVVVPPPPTYMIYYIFVGIGIIMSLSGILIFVLYKKKKMTPRDLYINTEVNPFYASHQYIPDDWEVARDCILQLGPLGQGSFGMVYEGILKGHMGVDTPCAIKTVNENATDRERVNFLSEASVMKEFDTFHVVHLLGVCSHGQPALVVMELMKKGDLKSYLRAHRPEERNEEMLAYLQRIGVTGNASPPTYGRFYQMAIEIADGMAYLSAKKFVHRDLAARNCMVSDDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYASSSDVFSFGVVLWEMATLASQPYQGLSNEQVLRYVIDGGIMERPENCPDVLHKLMHRCWHHRPSARPSFLDIIAYLEPHSSNAHFKEVSFYHSEAGLQYREKDRKEKSQMDAAFVAEPLDQDHEDATTPLRVGDYQSGYKSNMDQNASLEQPAESPINIVEEQTAHSPFSLQSGFVVSSTPDAPTAGGISHDDTSGYVQPDADALASTGADRGYEIYDPSPNFAELPTSRSGSTGAGGGDGKLSGEQHLLPRKSRRTPIIMSSSMPDDVVSGGAGSLQPSTASAGSSNASSHTGGGSRGTSSLKKIMNRSILFNRPFFNHKRTGSNASHKSNSSITPSTCSNANLTPHPIATSNLGTIESGGSGSAGSYAGTPRFYTPAATPSIGGGGISDNPNYKLLDESIISGGTARSWNQNRGPGTMAAGLSDSEQATMLTISSLNPNYELMQPPSPTPSLRAYPNYVQMNEPAPVILSSMNPNYEQMQAPHAHLSSSDEEDLNENDDDCHEDIKMERMPLSRQKPRSQYKSSSQTPRSRSVSQNRKKNDQHTTPQQTASSAMAAAGNVSNILKENWLRQAASTNRPPPPNGFIGREA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias800-827Basic and acidic residues
Compositional bias1593-1621Polar residues
Compositional bias1837-1899Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH964232
EMBL· GenBank· DDBJ
EDW81456.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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