B4J3Q6 · B4J3Q6_DROGR
- ProteinCalcium-transporting ATPase
- GeneDgri\GH16765
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1042 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Catalytic activity
- Ca2+(in) + ATP + H2O = Ca2+(out) + ADP + phosphate + H+Ca2+ (in)CHEBI:29108
+ CHEBI:30616 + CHEBI:15377 = Ca2+ (out)CHEBI:29108+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378 - Mn2+(in) + ATP + H2O = Mn2+(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | Golgi membrane | |
Cellular Component | peroxisomal membrane | |
Cellular Component | plasma membrane | |
Cellular Component | sarcoplasmic reticulum | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | P-type calcium transporter activity | |
Molecular Function | P-type manganese transporter activity | |
Biological Process | calcium ion transport from cytosol to endoplasmic reticulum | |
Biological Process | Golgi calcium ion transmembrane transport | |
Biological Process | intracellular calcium ion homeostasis | |
Biological Process | peroxisomal membrane transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCalcium-transporting ATPase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Hawaiian Drosophila
Accessions
- Primary accessionB4J3Q6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endomembrane system ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 202-220 | Helical | |||
Transmembrane | 226-245 | Helical | |||
Transmembrane | 393-411 | Helical | |||
Transmembrane | 423-447 | Helical | |||
Transmembrane | 899-918 | Helical | |||
Transmembrane | 969-987 | Helical | |||
Transmembrane | 999-1017 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 34-69 | Disordered | |||
Compositional bias | 55-69 | Acidic residues | |||
Region | 85-104 | Disordered | |||
Domain | 148-222 | Cation-transporting P-type ATPase N-terminal | |||
Sequence similarities
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,042
- Mass (Da)114,450
- Last updated2008-09-23 v1
- MD5 ChecksumE6D4FD4A7AFD4202BC3C22F0B26C8A76
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 55-69 | Acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH916366 EMBL· GenBank· DDBJ | EDV97287.1 EMBL· GenBank· DDBJ | Genomic DNA |