B4I7R8 · B4I7R8_DROSE

Function

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site944-952ATP (UniProtKB | ChEBI)
Binding site971ATP (UniProtKB | ChEBI)
Active site1063Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentbasal plasma membrane
Cellular Componentcytoneme
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionepidermal growth factor receptor activity
Biological Processbehavioral response to ethanol
Biological Processborder follicle cell migration
Biological Processcell projection assembly
Biological Processchorion-containing eggshell pattern formation
Biological Processcompound eye cone cell differentiation
Biological Processdetermination of adult lifespan
Biological Processdetermination of genital disc primordium
Biological Processdorsal appendage formation
Biological Processdorsal closure, spreading of leading edge cells
Biological Processepithelial cell proliferation involved in Malpighian tubule morphogenesis
Biological Processestablishment of epithelial cell apical/basal polarity
Biological Processeye-antennal disc morphogenesis
Biological Processgerm-band shortening
Biological Processgerm-line stem cell population maintenance
Biological Processgonad development
Biological Processhaltere development
Biological Processheart process
Biological Processimaginal disc-derived wing vein morphogenesis
Biological Processimaginal disc-derived wing vein specification
Biological Processleg disc proximal/distal pattern formation
Biological Processlumen formation, open tracheal system
Biological Processmaintenance of epithelial cell apical/basal polarity
Biological Processmaintenance of epithelial integrity, open tracheal system
Biological Processmaternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded
Biological Processnegative regulation of apoptotic signaling pathway
Biological Processnegative regulation of compound eye retinal cell programmed cell death
Biological Processnegative regulation of G1/S transition of mitotic cell cycle
Biological Processnegative regulation of gene expression
Biological Processnotum cell fate specification
Biological Processnotum development
Biological Processoenocyte differentiation
Biological Processolfactory learning
Biological Processommatidial rotation
Biological Processoocyte axis specification
Biological Processperipheral nervous system development
Biological Processphotoreceptor cell fate determination
Biological Processpositive regulation of border follicle cell migration
Biological Processpositive regulation of cell division
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of imaginal disc growth
Biological Processpositive regulation of kinase activity
Biological Processpositive regulation of wound healing
Biological Processprotein phosphorylation
Biological ProcessR8 cell differentiation
Biological Processregulation of tube length, open tracheal system
Biological Processsalivary gland development
Biological Processsecond mitotic wave involved in compound eye morphogenesis
Biological Processsegment polarity determination
Biological Processspiracle morphogenesis, open tracheal system
Biological Processstem cell fate commitment
Biological Processtracheal outgrowth, open tracheal system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Receptor protein-tyrosine kinase
  • EC number

Gene names

    • Name
      Dsec\GM15842
    • ORF names
      Dsec_GM15842

Organism names

  • Taxonomic identifier
  • Strain
    • Rob3c / Tucson 14021-0248.25
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    B4I7R8

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane869-892Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-30
ChainPRO_500280681431-1425Receptor protein-tyrosine kinase

Interaction

Protein-protein interaction databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain938-1198Protein kinase
Region1265-1294Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,425
  • Mass (Da)
    159,588
  • Last updated
    2008-09-23 v1
  • Checksum
    CC701E8BB83241E4
MLLRRRNGPCPFPLLLLLLAHCTCIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLELTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYSKMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEGVCKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGECVPCNGPCPKTCPGVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERLEVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCISDCGFISNAYKFDNRTCKICHPECRTCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQCHPECNGCTGPGADDCKACRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASVEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIVEPDDYLQPKHLVLVTEPTARDEIPKLNRYCKDPSNKNSSTGDDETDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPNNNNNMNNPNQNNMAAVGVAAGYMDLIGVPVSVDNPEYLLNAQTLGVGESPIPTQTIGIPVMGVPGTMEVKVPMPGSEPTSSDHEYYNDTQRELQPLHRNRNTETRV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH480824
EMBL· GenBank· DDBJ
EDW56643.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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