B4F9A4 · DMAS1_MAIZE
- ProteinDeoxymugineic acid synthase 1
- GeneDMAS1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids314 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met. Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
Catalytic activity
- 2'-deoxymugineate + NAD+ = 3''-deamino-3''-oxonicotianamine + H+ + NADH
pH Dependence
Optimum pH is 8-9.
Pathway
Siderophore biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 44 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Active site | 49 | Proton donor | ||||
Sequence: Y | ||||||
Binding site | 112 | substrate | ||||
Sequence: H | ||||||
Binding site | 158-159 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: CN | ||||||
Binding site | 180 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 258-266 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: FDEGRMKEN | ||||||
Binding site | 273-281 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: ELSEEERQR |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3''-deamino-3''-oxonicotianamine reductase activity | |
Molecular Function | aldose reductase (NADPH) activity | |
Biological Process | cellular response to zinc ion starvation | |
Biological Process | response to iron ion starvation | |
Biological Process | siderophore biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDeoxymugineic acid synthase 1
- EC number
- Short namesZmDMAS1
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea
Accessions
- Primary accessionB4F9A4
- Secondary accessions
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000442300 | 1-314 | Deoxymugineic acid synthase 1 | |||
Sequence: MSATGRAPCGLPRIGLGTAVQGPRPDPVRAAVLRAIQLGYRHFDTAAHYATEAPIGEAAAEAVRTGLVASREDLFVTSKVWCADAHRDRVLPALRRTLSNLQMEYVDLYMVHWPVTMKAGRFTAPFTPEDFEPFDMRAVWEAMEECHRLGLAKAIGVCNFSCKKLETLLSFATIPPVVNQVEINPVWQQRKLREFCRAKGIQLCAYSPLGAKGTHWGSDSVMDSGVLHEIAKSKGKTVAQVCLRWVYEQGDCLIVKSFDEGRMKENLDIVDWELSEEERQRISKIPQRKINQGRRYVSEHGPYKSFEELWDGEI |
Proteomic databases
Expression
Induction
Up-regulated under iron-deficient conditions in root tissues.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length314
- Mass (Da)35,378
- Last updated2008-09-23 v1
- Checksum14A3565818B357ED
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A804LGS9 | A0A804LGS9_MAIZE | 778439 | 259 | ||
A0A804LGT0 | A0A804LGT0_MAIZE | 778439 | 302 |
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 14 | in Ref. 1; BAF03164 | ||||
Sequence: I → V | ||||||
Sequence conflict | 311 | in Ref. 1; BAF03164 | ||||
Sequence: D → A |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB269909 EMBL· GenBank· DDBJ | BAF03164.1 EMBL· GenBank· DDBJ | mRNA | ||
CM007647 EMBL· GenBank· DDBJ | ONL95785.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT033692 EMBL· GenBank· DDBJ | ACF78697.1 EMBL· GenBank· DDBJ | mRNA |