B4DXZ6 · B4DXZ6_HUMAN
- ProteinFMR1 autosomal homolog 1
- GeneFXR1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids608 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic ribonucleoprotein granule | |
Cellular Component | cytosol | |
Cellular Component | postsynapse | |
Molecular Function | mRNA binding | |
Biological Process | muscle organ development | |
Biological Process | regulation of translation |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionB4DXZ6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 543 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 388 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 390 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 393 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 396 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 398 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 400 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 407 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 410 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 419 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 451 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 464 | PRIDE | Phosphotyrosine | ||||
Sequence: Y | |||||||
Modified residue (large scale data) | 470 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 472 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 478 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 483 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 572 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 574 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 584 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 598 | PRIDE | Phosphothreonine | ||||
Sequence: T |
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-37 | Agenet-like | ||||
Sequence: MVTEGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLP | ||||||
Domain | 50-102 | Agenet-like | ||||
Sequence: DEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPV | ||||||
Region | 368-517 | Disordered | ||||
Sequence: RSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVN | ||||||
Compositional bias | 396-431 | Basic and acidic residues | ||||
Sequence: SETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGG | ||||||
Compositional bias | 454-476 | Polar residues | ||||
Sequence: SVLKDPDSNPYSLLDNTESDQTA | ||||||
Region | 532-608 | Disordered | ||||
Sequence: ESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS | ||||||
Compositional bias | 542-562 | Basic and acidic residues | ||||
Sequence: RETLAKNKKEMAKDVIEEHGP | ||||||
Compositional bias | 581-595 | Basic and acidic residues | ||||
Sequence: LQRTPGEEKINTLKE |
Sequence similarities
Belongs to the FMR1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length608
- Mass (Da)68,327
- Last updated2008-09-23 v1
- Checksum100402E601FE5E2A
Computationally mapped potential isoform sequences
There are 13 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P51114 | FXR1_HUMAN | FXR1 | 621 | ||
C9IZ22 | C9IZ22_HUMAN | FXR1 | 94 | ||
C9J5B4 | C9J5B4_HUMAN | FXR1 | 75 | ||
E7EU85 | E7EU85_HUMAN | FXR1 | 454 | ||
C9JY20 | C9JY20_HUMAN | FXR1 | 123 | ||
C9JYQ6 | C9JYQ6_HUMAN | FXR1 | 19 | ||
C9JZE0 | C9JZE0_HUMAN | FXR1 | 119 | ||
C9JAJ4 | C9JAJ4_HUMAN | FXR1 | 151 | ||
H7C4S4 | H7C4S4_HUMAN | FXR1 | 246 | ||
E9PFF5 | E9PFF5_HUMAN | FXR1 | 490 | ||
A0A8V8TNP6 | A0A8V8TNP6_HUMAN | FXR1 | 568 | ||
A0A8V8TM97 | A0A8V8TM97_HUMAN | FXR1 | 54 | ||
A0A8V8TMQ1 | A0A8V8TMQ1_HUMAN | FXR1 | 650 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 396-431 | Basic and acidic residues | ||||
Sequence: SETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGG | ||||||
Compositional bias | 454-476 | Polar residues | ||||
Sequence: SVLKDPDSNPYSLLDNTESDQTA | ||||||
Compositional bias | 542-562 | Basic and acidic residues | ||||
Sequence: RETLAKNKKEMAKDVIEEHGP | ||||||
Compositional bias | 581-595 | Basic and acidic residues | ||||
Sequence: LQRTPGEEKINTLKE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC008009 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC068638 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC108734 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AK302197 EMBL· GenBank· DDBJ | BAG63558.1 EMBL· GenBank· DDBJ | mRNA |