B4DXZ6 · B4DXZ6_HUMAN

  • Protein
    FMR1 autosomal homolog 1
  • Gene
    FXR1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasmic ribonucleoprotein granule
Cellular Componentcytosol
Cellular Componentpostsynapse
Molecular FunctionmRNA binding
Biological Processmuscle organ development
Biological Processregulation of translation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • FMR1 autosomal homolog 1
    • cDNA FLJ58644, highly similar to Fragile X mental retardation syndrome-related protein 1

Gene names

    • Name
      FXR1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B4DXZ6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 543 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)388PRIDEPhosphothreonine
Modified residue (large scale data)390PRIDEPhosphoserine
Modified residue (large scale data)393PRIDEPhosphoserine
Modified residue (large scale data)396PRIDEPhosphoserine
Modified residue (large scale data)398PRIDEPhosphothreonine
Modified residue (large scale data)400PRIDEPhosphoserine
Modified residue (large scale data)407PRIDEPhosphoserine
Modified residue (large scale data)410PRIDEPhosphoserine
Modified residue (large scale data)419PRIDEPhosphoserine
Modified residue (large scale data)451PRIDEPhosphoserine
Modified residue (large scale data)464PRIDEPhosphotyrosine
Modified residue (large scale data)470PRIDEPhosphothreonine
Modified residue (large scale data)472PRIDEPhosphoserine
Modified residue (large scale data)478PRIDEPhosphothreonine
Modified residue (large scale data)483PRIDEPhosphoserine
Modified residue (large scale data)572PRIDEPhosphoserine
Modified residue (large scale data)574PRIDEPhosphoserine
Modified residue (large scale data)584PRIDEPhosphothreonine
Modified residue (large scale data)598PRIDEPhosphothreonine

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain1-37Agenet-like
Domain50-102Agenet-like
Region368-517Disordered
Compositional bias396-431Basic and acidic residues
Compositional bias454-476Polar residues
Region532-608Disordered
Compositional bias542-562Basic and acidic residues
Compositional bias581-595Basic and acidic residues

Sequence similarities

Belongs to the FMR1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    608
  • Mass (Da)
    68,327
  • Last updated
    2008-09-23 v1
  • Checksum
    100402E601FE5E2A
MVTEGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGPNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADYISRAESQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGVS

Computationally mapped potential isoform sequences

There are 13 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P51114FXR1_HUMANFXR1621
C9IZ22C9IZ22_HUMANFXR194
C9J5B4C9J5B4_HUMANFXR175
E7EU85E7EU85_HUMANFXR1454
C9JY20C9JY20_HUMANFXR1123
C9JYQ6C9JYQ6_HUMANFXR119
C9JZE0C9JZE0_HUMANFXR1119
C9JAJ4C9JAJ4_HUMANFXR1151
H7C4S4H7C4S4_HUMANFXR1246
E9PFF5E9PFF5_HUMANFXR1490
A0A8V8TNP6A0A8V8TNP6_HUMANFXR1568
A0A8V8TM97A0A8V8TM97_HUMANFXR154
A0A8V8TMQ1A0A8V8TMQ1_HUMANFXR1650

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias396-431Basic and acidic residues
Compositional bias454-476Polar residues
Compositional bias542-562Basic and acidic residues
Compositional bias581-595Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC008009
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC068638
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC108734
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AK302197
EMBL· GenBank· DDBJ
BAG63558.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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