B4DX19 · B4DX19_HUMAN

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 2 calcium ions per subunit.

Features

Showing features for binding site, active site.

135550100150200250300350
TypeIDPosition(s)Description
Binding site53Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site54Ca2+ 2 (UniProtKB | ChEBI)
Active site115Proton acceptor
Binding site117Ca2+ 2 (UniProtKB | ChEBI)
Binding site168Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site169Ca2+ 2 (UniProtKB | ChEBI)
Binding site224Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site269Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site270Ca2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionacyl-L-homoserine-lactone lactonohydrolase activity
Molecular Functionarylesterase activity
Molecular Functionmetal ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Paraoxonase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B4DX19

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-30
ChainPRO_502994183831-355Paraoxonase
Disulfide bond42↔353In form B
Glycosylation253N-linked (GlcNAc...) asparagine
Glycosylation270N-linked (GlcNAc...) asparagine
Glycosylation324N-linked (GlcNAc...) asparagine

Post-translational modification

Glycosylated.

Keywords

Family & Domains

Sequence similarities

Belongs to the paraoxonase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    39,721
  • Last updated
    2008-09-23 v1
  • Checksum
    B579F535E44B59E2
MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELETGSEDMEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK301772
EMBL· GenBank· DDBJ
BAG63231.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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