B4DT20 · B4DT20_HUMAN

  • Protein
    MICOS complex subunit MIC60
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane

Names & Taxonomy

Protein names

  • Recommended name
    MICOS complex subunit MIC60
  • Alternative names
    • Mitofilin

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B4DT20

Subcellular Location

Mitochondrion inner membrane
; Single-pass membrane protein

Keywords

Interaction

Subunit

Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil203-237
Coiled coil299-326

Sequence similarities

Belongs to the MICOS complex subunit Mic60 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    659
  • Mass (Da)
    73,156
  • Last updated
    2008-09-23 v1
  • MD5 Checksum
    8211A6AD819E656FAA7F9F15A73685FA
MLRACQLSGVTAAAQSCLCGKFVLRPLRPCRRYSTSGSSGLTTGKIAGAGLLFVGGGIGGTILYAKWDSHFRESVEKTIPYSDKLFEMVLGPAAYNVPLPKKSIQSGPLKISSVSEVMKESKQPASQLQKQKGDTPASATALAKSLEDVLRQTASVTLQAIAAQNAAVQAVNAHSNILKAAMDNSEIAGEKKSAQWRTVEGALKERRKAVDEAADALLKAKEELEKMKSVIENAKKKEVAGAKPHITAAEGKLHNMIVDLDNVVQARDDFKRELDSITPEVLPGWKGMSVSDLADKLSTDDLNSLIAHAHRRIDQLNRELAEQKATEKQHITLALEKQKLEEKRAFDSAVAKALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVEAIKANCSDNEFTQALTAAIPPESLTRGVYSEETLRARFYAVQKLARRVAMIDETRNSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYCIEHGDLELAAKFVNQLKGESRRVAQDWLKEARMTLETKQIVEILTAYASAVGIGTTQVQPE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK300017
EMBL· GenBank· DDBJ
BAG61832.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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