B4DKM6 · B4DKM6_HUMAN

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 2 calcium ions per subunit.

Features

Showing features for binding site, active site.

136350100150200250300350
TypeIDPosition(s)Description
Binding site74Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site75Ca2+ 1 (UniProtKB | ChEBI); catalytic
Active site135Proton acceptor
Binding site137Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site176Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site177Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site232Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site277Ca2+ 1 (UniProtKB | ChEBI); catalytic
Binding site278Ca2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentextracellular region
Cellular Componentmembrane
Molecular Functionacyl-L-homoserine-lactone lactonohydrolase activity
Molecular Functionarylesterase activity
Molecular Functionmetal ion binding
Biological Processresponse to toxic substance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Paraoxonase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    B4DKM6

Subcellular Location

Membrane
; Peripheral membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-43Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond, glycosylation.

TypeIDPosition(s)Description
Disulfide bond63↔361In form B
Glycosylation278N-linked (GlcNAc...) asparagine
Glycosylation332N-linked (GlcNAc...) asparagine

Post-translational modification

Glycosylated.

Keywords

Proteomic databases

Interaction

Subunit

Homotrimer.

Family & Domains

Sequence similarities

Belongs to the paraoxonase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    40,028
  • Last updated
    2008-09-23 v1
  • Checksum
    AC841159D01021D2
MAPPTELLARPERGSAPGSRAMGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPGARELRISRGFDLASFNPHGISTFIDNEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK296636
EMBL· GenBank· DDBJ
BAG59238.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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