Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis.
- AnnotationThe DI/VF sequence motif of BDAJB6 acts as a crucial switch that determines the state of the entire Hsp40-Hsp70 machine and eventually chaperone activity and cell death or survival.
- CategoriesFamily & Domains, Interaction, Structure
- SourceGeneRif: 3337