B3TZC1 · B3TZC1_CHICK
- ProteinPNPLA7
- GenePNPLA7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1324 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + H+ + sn-glycerol 3-phosphocholineThis reaction proceeds in the forward direction.
- 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = H+ + hexadecanoate + sn-glycerol 3-phosphateThis reaction proceeds in the forward direction.
- 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = H+ + hexadecanoate + sn-glycerol 3-phosphocholineThis reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 969 | Nucleophile | ||||
Sequence: S | ||||||
Active site | 1089 | Proton acceptor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | lysophospholipase activity | |
Biological Process | lipid catabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus
Accessions
- Primary accessionB3TZC1
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass type III membrane protein
Membrane ; Single-pass type III membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 30-53 | Helical | ||||
Sequence: MLTGIAIGAAVALFLIGIVVFVIY |
Keywords
- Cellular component
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 165-292 | Cyclic nucleotide-binding | ||||
Sequence: VLGHFEKPLFLELCKHMFFVQLHEGEYIFRPGQLDNSIYVVQDGKLEVCVQESDGTEVIVKEVLAGDSVHSLLSILDVITGHPAPYKTVSARAATPSNILRLPASAFQDVFQKYPETLVRVVQIIMVR | ||||||
Region | 328-400 | Disordered | ||||
Sequence: TSGGSSSKAAKRQVSSVSEEERGEKFEKSGEASEMDTLKNSGTENPEHIFRRSLSSPPSTETSGTSSGAKSDM | ||||||
Compositional bias | 341-361 | Basic and acidic residues | ||||
Sequence: VSSVSEEERGEKFEKSGEASE | ||||||
Compositional bias | 362-397 | Polar residues | ||||
Sequence: MDTLKNSGTENPEHIFRRSLSSPPSTETSGTSSGAK | ||||||
Domain | 482-574 | Cyclic nucleotide-binding | ||||
Sequence: LNDRVTLHQVTAGTVLSRQGDQDVNVCFVVSGMLHVYQQKVDSEEDTCLFITHPGELVGQLAVLTGEPLIFTIKANRDCSFLSISKSHFYEIM | ||||||
Domain | 602-707 | Cyclic nucleotide-binding | ||||
Sequence: ALDWMEVEAGRAVYRQGDKSDCTYIVLNGRLRSVIRMDDGKKHLTGEYGRGDLIGVVEALTHQPRATTVHAVRDSELAKLPEGALTSIKRKFPQVVTRLIHLLGEK | ||||||
Domain | 936-1102 | PNPLA | ||||
Sequence: LVLGGGGARGCSQVGLIRALIEAGIPVDMIGGTSIGAFMSALYAEERSYNQMRIKARQWAMVMNSVFKTILDLTYPITSMFSGAAFNNSISNIFKDKQIEDLWIPYFTITTDITASAMRVHTDGSLWRYIRASMSLSGYMPPLCDPKDGHLLMDGGYVNNLPADVAR | ||||||
Motif | 940-945 | GXGXXG | ||||
Sequence: GGGARG | ||||||
Motif | 967-971 | GXSXG | ||||
Sequence: GTSIG | ||||||
Motif | 1089-1091 | DGA/G | ||||
Sequence: DGG | ||||||
Compositional bias | 1290-1312 | Basic and acidic residues | ||||
Sequence: NQAEDDSDSDEDVQIRKRKNLPK | ||||||
Region | 1290-1324 | Disordered | ||||
Sequence: NQAEDDSDSDEDVQIRKRKNLPKVDCQASSTGEPA |
Sequence similarities
Belongs to the NTE family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,324
- Mass (Da)147,730
- Last updated2008-09-02 v1
- Checksum616B053F54F1F151
Computationally mapped potential isoform sequences
There are 8 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8V1AG25 | A0A8V1AG25_CHICK | PNPLA7 | 1363 | ||
A0A8V1AHX7 | A0A8V1AHX7_CHICK | PNPLA7 | 1286 | ||
A0A8V1AG15 | A0A8V1AG15_CHICK | PNPLA7 | 1321 | ||
A0A8V1AG20 | A0A8V1AG20_CHICK | PNPLA7 | 1259 | ||
A0A1D5NTC9 | A0A1D5NTC9_CHICK | PNPLA7 | 1273 | ||
A0A8V1A5T1 | A0A8V1A5T1_CHICK | PNPLA7 | 1338 | ||
A0A8V1ADH1 | A0A8V1ADH1_CHICK | PNPLA7 | 1271 | ||
A0A8V1AAQ2 | A0A8V1AAQ2_CHICK | PNPLA7 | 1280 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 341-361 | Basic and acidic residues | ||||
Sequence: VSSVSEEERGEKFEKSGEASE | ||||||
Compositional bias | 362-397 | Polar residues | ||||
Sequence: MDTLKNSGTENPEHIFRRSLSSPPSTETSGTSSGAK | ||||||
Compositional bias | 1290-1312 | Basic and acidic residues | ||||
Sequence: NQAEDDSDSDEDVQIRKRKNLPK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU419881 EMBL· GenBank· DDBJ | ACC91741.1 EMBL· GenBank· DDBJ | mRNA |