B3PNV4 · SYT_RHIE6

Function

function

Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

166850100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site347Zn2+ (UniProtKB | ChEBI)
Binding site398Zn2+ (UniProtKB | ChEBI)
Binding site530Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionthreonine-tRNA ligase activity
Molecular FunctiontRNA binding
Biological Processthreonyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Threonine--tRNA ligase
  • EC number
  • Alternative names
    • Threonyl-tRNA synthetase
      (ThrRS
      )

Gene names

    • Name
      thrS
    • Ordered locus names
      RHECIAT_CH0002285

Organism names

  • Taxonomic identifier
  • Strain
    • CIAT 652
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Rhizobium

Accessions

  • Primary accession
    B3PNV4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000986011-668Threonine--tRNA ligase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain1-64TGS
Region245-553Catalytic

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    668
  • Mass (Da)
    74,905
  • Last updated
    2008-09-02 v1
  • Checksum
    C3ABC8D2D3624A82
MSQAISLTFPDGSVRSFPAGATGKDVAESISKSLAKSAVAIAIDGAVRDLSDAVTDGKIEIITRKDGRALELIRHDAAHVMAEAVQELWPGTQVTIGPVIENGFYYDFAKNEPFTPDDLPKIEKKMKEIIARNAPFTKQIWSREKAKEVFAAKGEQYKVELVDAIPEGQDLKIYHQGDWFDLCRGPHMASTGQVGTAFKLMKVAGAYWRGDSNNAMLSRIYGTAWADQADLDNYLHMLAEAEKRDHRKLGREMDLFHFQEEGPGVVFWHGKGWRIFQTLVAYMRRRLAADYQEVNAPQVLDTSLWETSGHWGWYQENMFAVKSAHAMTHPEDKEADNRVFALKPMNCPGHVQIFKHGLKSYRELPIRLAEFGLVHRYEPSGALHGLMRVRGFTQDDAHIFCTDEQMAAECLKINDLILSVYEDFGFKEIVVKLSTRPEKRVGSDALWDRAEAVMTDVLKTIEAQSEGRIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIDSNSEKTQPVMIHRAICGSMERFLGILIENFAGHMPLWVSPLQVVVATITSEADAYGLEVAEALRDAGLNVETDFRNEKINYKIREHSVTKVPVIIVCGRKEAEERTVNIRRLGSQDQVSMGLDAAVESLTLEATPPDIRRKAEAKKAKAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001074
EMBL· GenBank· DDBJ
ACE91240.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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