CDT1 MCM7 and NUDT1 were shown to be up-regulated in hepatocellular carcinoma tissues and provide a more accurate diagnosis than alpha-fetal protein alone.
The results clearly demonstrate 7q21-22 amplification MCM7 and its intronic miR-25 are the major molecular switches involved in the complex oncogenic circuits of gastric cancer.
Results proved that MCM7 proliferative index is a better method for identifying patients with risk of recurrence in patients surgically resected for meningiomas compared with the traditional methods used in the current clinical practice.
MCM4 and MCM7 expression is significantly correlated with Ki-67 Bmi1 and cyclin E expression in esophageal adenocarcinoma squamous cell carcinoma and precancerous lesions.
We observed that lower levels of MCM7 correlate with reduced cell proliferation lower autophagic capacity and higher intracellular protein abundance phenotypes of aged and systemic sclerosis cells.
The A to G base change in SNP rs999885 of MCM7 may provide a protective effect on the prognosis of intermediate or advanced hepatocellular carcinoma in the Chinese.
Lymph node sections from 138 HL patients were immunohistochemically stained for cyclin D3 (CCND3) MCM2 and MCM7 aiming to investigate clinical outcome.
MCM7 expression was significantly higher in high-grade serous carcinomas than in serous borderline tumors or other histological subtypes of ovarian cancer.
RT-PCR and immunohistochemistry indicated positive expressions of Mcm7 mRNA and protein in normal oral mucosa precancerous lesions and oral squamous cell carcinoma.
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