B3KSE0 · B3KSE0_HUMAN
- ProteinHeme oxygenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids316 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe2+ + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | heme oxygenase (decyclizing) activity | |
Molecular Function | metal ion binding | |
Biological Process | heme oxidation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHeme oxygenase
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionB3KSE0
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 295-315 | Helical | ||||
Sequence: SLQFILAAGVALAAGLLAWYY |
Keywords
- Cellular component
Disease & Variants
Organism-specific databases
PTM/Processing
Proteomic databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-27 | Disordered | ||||
Sequence: MSAEVETSEGVDESEKKNSGALEKENQ | ||||||
Compositional bias | 9-27 | Basic and acidic residues | ||||
Sequence: EGVDESEKKNSGALEKENQ |
Sequence similarities
Belongs to the heme oxygenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length316
- Mass (Da)35,961
- Last updated2008-09-02 v1
- Checksum99896A34B53881AD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 9-27 | Basic and acidic residues | ||||
Sequence: EGVDESEKKNSGALEKENQ |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK093388 EMBL· GenBank· DDBJ | BAG52702.1 EMBL· GenBank· DDBJ | mRNA |