B3KRA9 · B3KRA9_HUMAN
- ProteinPhosphotransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids566 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-fructose + ATP = D-fructose 6-phosphate + ADP + H+This reaction proceeds in the forward direction.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrial outer membrane | |
Molecular Function | ATP binding | |
Molecular Function | D-glucose binding | |
Molecular Function | glucokinase activity | |
Molecular Function | glucosamine kinase activity | |
Molecular Function | mannokinase activity | |
Biological Process | glycolytic process | |
Biological Process | hexose metabolic process | |
Biological Process | inflammatory response | |
Biological Process | innate immune response | |
Biological Process | intracellular glucose homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphotransferase
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionB3KRA9
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion outer membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-191 | Hexokinase N-terminal | |||
Domain | 198-431 | Hexokinase C-terminal | |||
Domain | 442-545 | Hexokinase N-terminal | |||
Sequence similarities
Belongs to the hexokinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length566
- Mass (Da)63,356
- Last updated2008-09-02 v1
- MD5 Checksum62C1480CEE9BA281B8B3E6B8424415BE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK091267 EMBL· GenBank· DDBJ | BAG52321.1 EMBL· GenBank· DDBJ | mRNA |