B3KPE6 · B3KPE6_HUMAN
- ProteinZinc finger protein 608
- GeneZNF608
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids707 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | negative regulation of transcription by RNA polymerase II |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Hominoidea (apes) > Hominidae (great apes) > Homininae > Homo
Accessions
- Primary accessionB3KPE6
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,368 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 291 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 421 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 424 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 440 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 481 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 512 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 627 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 636 | PRIDE | Phosphothreonine | ||||
Sequence: T |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-23 | Disordered | ||||
Sequence: MSVNISTAGKGVDPNTVDTYDSG | ||||||
Region | 46-74 | Disordered | ||||
Sequence: QKFEMNNSTTTTSSSNSKDCGGPASSGAG | ||||||
Compositional bias | 50-67 | Polar residues | ||||
Sequence: MNNSTTTTSSSNSKDCGG | ||||||
Region | 89-237 | Disordered | ||||
Sequence: QASAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNPNSNSTSTSTSAATAGAGSCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYG | ||||||
Compositional bias | 149-181 | Polar residues | ||||
Sequence: MNSALGQSVSSGGSGNPNSNSTSTSTSAATAGA | ||||||
Compositional bias | 187-219 | Basic and acidic residues | ||||
Sequence: SKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQ | ||||||
Region | 260-295 | Disordered | ||||
Sequence: VAAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRI | ||||||
Compositional bias | 281-295 | Basic and acidic residues | ||||
Sequence: LVKKEEEEEESHRRI | ||||||
Region | 417-543 | Disordered | ||||
Sequence: RFCESPTSDLEMRGGRGRGKRARSAAAAPGSEASFTESRGLQNKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDNKPGKRVRTNSRSTPTTPQGKPETTFL | ||||||
Compositional bias | 490-513 | Polar residues | ||||
Sequence: IKASPSSTNKRKNKPPMELDLNSS | ||||||
Compositional bias | 524-543 | Polar residues | ||||
Sequence: RTNSRSTPTTPQGKPETTFL | ||||||
Domain | 555-578 | C2H2-type | ||||
Sequence: CPHPNCNKKYKHINGLRYHQAHAH | ||||||
Region | 623-669 | Disordered | ||||
Sequence: KAPASPGAGNPPGTPKGKRELMSNGPGSIIGAKAGKNSGKKKGLNNE |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length707
- Mass (Da)73,508
- Last updated2008-09-02 v1
- ChecksumF45EF679379AABE0
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9ULD9 | ZN608_HUMAN | ZNF608 | 1512 | ||
A2RRB2 | A2RRB2_HUMAN | ZNF608 | 447 | ||
A0A0C4DGB8 | A0A0C4DGB8_HUMAN | ZNF608 | 715 |
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 50-67 | Polar residues | ||||
Sequence: MNNSTTTTSSSNSKDCGG | ||||||
Compositional bias | 149-181 | Polar residues | ||||
Sequence: MNSALGQSVSSGGSGNPNSNSTSTSTSAATAGA | ||||||
Compositional bias | 187-219 | Basic and acidic residues | ||||
Sequence: SKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQ | ||||||
Compositional bias | 281-295 | Basic and acidic residues | ||||
Sequence: LVKKEEEEEESHRRI | ||||||
Compositional bias | 490-513 | Polar residues | ||||
Sequence: IKASPSSTNKRKNKPPMELDLNSS | ||||||
Compositional bias | 524-543 | Polar residues | ||||
Sequence: RTNSRSTPTTPQGKPETTFL | ||||||
Non-terminal residue | 707 | |||||
Sequence: D |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC112196 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC113398 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AK056247 EMBL· GenBank· DDBJ | BAG51658.1 EMBL· GenBank· DDBJ | mRNA |