B3FL75 · B3FL75_SHEEP
- ProteinGlycogen synthase kinase-3 beta
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids420 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- ATP + L-seryl-[tau protein] = ADP + H+ + O-phospho-L-seryl-[tau protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | axon | |
Cellular Component | beta-catenin destruction complex | |
Cellular Component | cytosol | |
Cellular Component | glutamatergic synapse | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | beta-catenin binding | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | tau-protein kinase activity | |
Biological Process | extrinsic apoptotic signaling pathway in absence of ligand | |
Biological Process | glycogen metabolic process | |
Biological Process | insulin receptor signaling pathway | |
Biological Process | negative regulation of canonical Wnt signaling pathway | |
Biological Process | negative regulation of developmental process | |
Biological Process | regulation of microtubule cytoskeleton organization | |
Biological Process | regulation of neuron projection development |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycogen synthase kinase-3 beta
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Caprinae > Ovis
Accessions
- Primary accessionB3FL75
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-25 | Polar residues | ||||
Sequence: MSGRPRTTSFAESCKPVQQPSAFGS | ||||||
Region | 1-53 | Disordered | ||||
Sequence: MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQE | ||||||
Domain | 56-340 | Protein kinase | ||||
Sequence: YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF | ||||||
Region | 385-420 | Disordered | ||||
Sequence: QAAASTPSNTTAASDANAGDRGQTNNAASASASDSS | ||||||
Compositional bias | 386-420 | Polar residues | ||||
Sequence: AAASTPSNTTAASDANAGDRGQTNNAASASASDSS |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length420
- Mass (Da)46,717
- Last updated2008-07-22 v1
- Checksum4EDC2560FEABCEC3
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-25 | Polar residues | ||||
Sequence: MSGRPRTTSFAESCKPVQQPSAFGS | ||||||
Compositional bias | 386-420 | Polar residues | ||||
Sequence: AAASTPSNTTAASDANAGDRGQTNNAASASASDSS |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EU239382 EMBL· GenBank· DDBJ | ABY65117.1 EMBL· GenBank· DDBJ | mRNA |