B3EKJ5 · FLUC_CHLPB

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

1128102030405060708090100110120
TypeIDPosition(s)Description
Binding site78Na+ (UniProtKB | ChEBI); structural
Binding site81Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • Ordered locus names
      Cphamn1_0200

Organism names

Accessions

  • Primary accession
    B3EKJ5

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1-21Helical
Transmembrane45-65Helical
Transmembrane70-90Helical
Transmembrane99-119Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001251171-128Fluoride-specific ion channel FluC

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    128
  • Mass (Da)
    13,645
  • Last updated
    2008-07-22 v1
  • Checksum
    820C16769A1CAA00
MPERYAALLLVGAGGFVGATARFLVALVLPFIGTGFPFGTLAVNLAGCFLIGFISQLSVSSSLVSPELRLLLATGFCGGFTTFSSYMYEIMSLLRDGEIFYSTLYLLGSIVGGILCLYFGMQLAKLWA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001101
EMBL· GenBank· DDBJ
ACE03173.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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