B3E6Z9 · B3E6Z9_TRIL1
- ProteinBifunctional uridylyltransferase/uridylyl-removing enzyme
- GeneglnD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids900 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- [protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate
- [protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + UMP + H+
Cofactor
Activity regulation
Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | [protein-PII] uridylyltransferase activity | |
Molecular Function | phosphoric diester hydrolase activity | |
Biological Process | regulation of nitrogen utilization |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameBifunctional uridylyltransferase/uridylyl-removing enzyme
- Short namesUTase/UR
- Alternative names
Including 2 domains:
- Recommended name[Protein-PII] uridylyltransferase
- EC number
- Short namesPII uridylyltransferase ; UTase
- Recommended name[Protein-PII]-UMP uridylyl-removing enzyme
- EC number
- Short namesUR
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Trichlorobacter
Accessions
- Primary accessionB3E6Z9
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-359 | Uridylyltransferase | ||||
Sequence: MPVHPISAAAIFSAGDQRSFEEQRPEILEACKQFITSSHEEIRQRHAAGASGTEVVHQLSAVMDAMVSTLFNGILGLMGADGKRLTGHLTLAAVGGYGRGELNPYSDVDIMFLHDGSVPVEAVEAFAQKLLYFLWDLRLDVGYSVRTPADCVEMAAQDTTIKTALIDCRYLAGHQPLFATLRKTVYSQILPKASDKFIKEKIAEMRRRRDKYGATIYLLEPNIKEGEGGLRDLQTALWVAQVKYKFDNPKELVIKGVLSEAELEVYHSALDHLWRMRNELHFHTRRKSDQMNFDLQVHLATFLGYKDRGKVLAVEDFMRDYYRHAARVEHFSSTLTSRCVWRDEGAAKILGYFVRRPVG | ||||||
Domain | 474-590 | HD | ||||
Sequence: VDIHTLFAVEQMEKILSGELKKELPLPCAIARQIGKRELLILSILFHDIGKGEGGGHADKGADMIPTIARRMGLSKEDSERLEFLVRQHLVFAHISQRRDLTDERMIMQFARQMVTS | ||||||
Domain | 714-799 | ACT | ||||
Sequence: SFTICTFDTHGLFSKITGVMAANGINILGAQIFTGKNGKILDILQVNSAQGFLITDAARWQKVEADMADVLHGTVQVSDLVHRRQR | ||||||
Domain | 827-900 | ACT | ||||
Sequence: VIDIYAHDKVGLLYLITSTINQLGLYIGVSKISTKVDQVADVFYVRDIFGHKIFAEDKLEEIRTSLSWAIDDWQ |
Domain
Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
Sequence similarities
Belongs to the GlnD family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length900
- Mass (Da)102,659
- Last updated2008-07-22 v1
- Checksum26B83E5B12DA177A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001089 EMBL· GenBank· DDBJ | ACD96404.1 EMBL· GenBank· DDBJ | Genomic DNA |