B3E2D7 · B3E2D7_TRIL1
- ProteindTTP/UTP pyrophosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids199 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- UTP + H2O = UMP + diphosphate + H+
Cofactor
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 15 | Important for substrate specificity | ||||
Sequence: R | ||||||
Active site | 73 | Proton acceptor | ||||
Sequence: D | ||||||
Site | 74 | Important for substrate specificity | ||||
Sequence: T | ||||||
Site | 158 | Important for substrate specificity | ||||
Sequence: Q |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | dTTP diphosphatase activity | |
Molecular Function | UTP diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedTTP/UTP pyrophosphatase
- EC number
- Short namesdTTPase/UTPase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Trichlorobacter
Accessions
- Primary accessionB3E2D7
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length199
- Mass (Da)21,520
- Last updated2008-07-22 v1
- Checksum5C694DF8D51AB64B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001089 EMBL· GenBank· DDBJ | ACD94190.1 EMBL· GenBank· DDBJ | Genomic DNA |