B3E2D7 · B3E2D7_TRIL1

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site15Important for substrate specificity
Active site73Proton acceptor
Site74Important for substrate specificity
Site158Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • Ordered locus names
      Glov_0462

Organism names

Accessions

  • Primary accession
    B3E2D7

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    199
  • Mass (Da)
    21,520
  • Last updated
    2008-07-22 v1
  • Checksum
    5C694DF8D51AB64B
MAATDPVVLASASPRRSELLELAGIRFRVAPADIPEEPMPGEEAVEHALRLAEEKARAAAGREADGQFFIGADTIVVLDGRIMGKPTDQNDAVRMLTELSGKGHEVVTAYAVLDKQSNVCIKRAVRTQVVFKQLSEQEISDYVKTGCPMDKAGAYAIQGGAAHFVREIHGSYTNVVGLPTCELVETLHTIGAWPKEEQH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001089
EMBL· GenBank· DDBJ
ACD94190.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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